I-Dihydrotestosterone kwabesifazane nakwabesilisa: imisebenzi, izimbangela zokwanda nokuncipha

I-Dihydrotestosterone iyinhlangano enamandla yamadoda ocansi abesilisa. Kuma-men, ihlanganiswa isenzo se-enzyme 5-alpha reductase ku-testosterone. Iningi le-dihydrotestosterone likhiqizwa kuma-testes. Emzimbeni wesifazane, enye i-hormone, okungukuthi i-androstenedione, isetshenziselwa ukwakha i-dihydrotestosterone. Ikhiqizwa yizindlala ze-adrenal.

Ingxenye encane ikhiqizwa amaqanda. Ezidalwa ezingamaduna, i-DHT inquma izici zokukhula komzimba kwintsha ngesikhathi sokuthomba. Le-hormone inesibopho se-potency nokuziphatha kocansi, ukuthuthukiswa kwendlala yesibindi kanye nezitho zangasese. Izinga eliphakeme kakhulu laleli hormone libonakala ezithombeni zezinwele nakwisikhumba sangasese. Uma i-dihydrotestosterone iphakanyisiwe emzimbeni womuntu, izifo ezahlukahlukene zingakhula ngenxa yalokhu.

Indima ye-dihydrotestosterone emzimbeni womuntu

Ngaphambi kokubheka izimbangela zokukhuphuka kwe-dihydrotestosterone emadodeni nakwabesifazane, kubalulekile ukuba nombono ojwayelekile weqhaza laleli hormone emzimbeni womuntu. I-Dihydrotestosterone, njengamanye ama-hormone amaningi esilisa, inomphumela oqondile ekukhuleni komzimba wenduna, ukuba khona kwezinwele emzimbeni nasebusweni, ukwakheka nokukhula kwezitho zangasese kanye nendlala ye-prostate, indlela yokuziphatha kwezocansi, njll.

Amaphesenti aphakeme kakhulu ale hormone akhiwa ezicutshini ezitholakala ngaphandle kwemingcele yama-testes. Okuqukethwe okuphezulu kakhulu kwe-dihydrotestosterone emadodeni, njengoba sekuphawuliwe, kubhekwa esikhunjeni sezitho zokuzala kanye nezinhlamvu zezinwele.

Emadodeni, le hormone inomphumela ovuselelayo ekwandeni kwamaseli we-Prostate. Esimweni lapho okuqukethwe yile hormone kuphambuka kokujwayelekile, kuvela izifo ezahlukahlukene, kufaka phakathi isimila se-Prostate. Uma izinga le-dihydrotestosterone emadodeni liphezulu kunokwejwayelekile, khona-ke iziguli ezinjalo zivame ukubekwa kuma-inhibitors we-5-alpha reductase. Izidakamizwa ezinjalo zivimbela ukuvela kwe-5-alpha reductase, ngenxa yokuthi okuqukethwe kwe-dihydrotestosterone egazini lamadoda kuncipha. Isimo esijwayelekile kubantu besilisa sincike eminyakeni yobudala kanye nezinye izinto okufanele zinakwe lapho kudluliswa ukuhlaziywa.

Emzimbeni wesifazane, ukukhiqizwa kwe-dihydrotestosterone kwenziwa ngaphakathi kwezicubu zezindlala ze-adrenal. Phakathi kwama-androgens angamaduna kukhona ama-hormone angama-5, kuwo kuphela ama-testosterone ne-dihydrotestosterone anomthelela oqondile emzimbeni. Ama-3 ama-hormone asele angaphansi kwesigaba sama-pro-hormone, okungukuthi, aqala ukuthinta umzimba kuphela ngemuva kokuthi "aguqulwe" abe yi-testosterone.

Uma i-dihydrotestosterone emzimbeni wowesifazane iba phezulu kunezinga elivumelekile, intombazane izoqala ukukhulisa izimpawu ze-hyperandrogenism, ezinjengokuthi:

• I-hirsutism yisifo lapho izinwele zikhula khona kakhulu futhi lapho abesifazane bengaveli khona,
• induna
• ukwanda okukhulu kosayizi be-clitoris.

Uma i-hormone igcinwa njalo ngaphezulu kwendlela evamile ebusheni, amantombazane angathola ukuhlukunyezwa kwamathambo (kukhula ngohlobo lowesilisa), ukungabi bikho kokuya esikhathini noma ukuphazamiseka komjikelezo, iphimbo lingaba mude. Kwabesifazane asebekhulile, okuqukethwe kwe-dihydrotestosterone ephakeme kunokwejwayelekile kungaholela ekukhuleni kokuzala nokungazalwa.

Uma i-hormone ingenayo ngobuningi obanele, amalungiselelo abalulekile angabekwa esigulini, ngemuva kokusebenzisa kwayo okuzoba ngaphezulu. Ukuphambuka kokuqukethwe kwe-dihydrotestosterone kusuka kokujwayelekile kungazalwa kabusha noma kutholakale.

Kwabesifazane nabesilisa, ukukhula kwe-dihydrotestosterone ngenhla okujwayelekile kuholela ekunciphiseni ukukhula kwezinwele, ukuwohloka kwesimo sabo ne-alopecia.

Imvelo nokuphambuka

Ukuthola okuqukethwe kwe-dihydrotestosterone esegazini lamadoda nabesifazane, kwenziwa ukuhlola kwegazi kwe-venous. Ekuhambeni kwalokhu kuhlaziywa, i-serum ye-DHT inqunywa indlela ye-enzyme immunoassay. Okujwayelekile kwabesifazane nabesilisa kuyahlukahluka ngokuya ngeminyaka.

• nge-hypergonadism,
• ngenkathi ngiphuza izidakamizwa ze-hormonal,
• nge-prostate adenoma,
• ngesikhathi sokukhulelwa kwabesifazane,
• phambi kwe-neoplasms kuma-gonads nezindlala ze-adrenal,
• nge-hirsutism.

Ukucacisa izizathu zokuthi kungani izinga le-hormone liphakanyisiwe, kuthunyelwa ukuhlaziywa okukhethekile. Lokhu kuhlaziya kungabekwa kumacala alandelayo:

• ngokuqukethwe okuphansi kwama-androgens,
• ngezinga eliphansi lokunciphisa kabusha i-5-alpha,
• ngokwehla kwesifiso sobulili kanye nokwephulwa kwe-potency,
• phambi kwezimpawu ezibonakaliswa i-prostatic hyperplasia (ukuchama okungahambi kahle, i-prostate eyandisiwe, njll.),
• ngesikhathi sokwelashwa ngemithi equkethe i-5-alpha-reductase inhibitors,
• ngokuzonda okusheshayo,
• ngokuncipha kosayizi wamalunga wamasende, ipenisi encane ngokungemthetho, ukungabikho kwezinwele emaphethelweni nakuma-pubis,
• ngokwephula umjikelezo wokuya esikhathini, ukuba khona kwezinduna nezimpawu ze-seborrhea,
• intsha ngesikhathi sokuthomba.

I-Dihydrotestosterone ne-testosterone zingama-hormone axhunyiwe, ngakho-ke, njengomthetho, okuqukethwe okuqukethwe okokuqala nokwesibili kuhlolwa ngasikhathi sinye.

Isebenzisa ukuhlaziya ukuthola izifo ezahlukahlukene

Uma izinga le-dihydrotestosterone esegazini liphakanyisiwe, lokhu kungakhombisa ukuba khona kwezifo ezithile. Ezimweni ezinjalo, ukuze kuqinisekiswe ukutholakala kwale nkinga, kuhlolisiswa okwenzelwe i-DHT esegazini. Phakathi kwezifo eziholela ekwandeni kokuqukethwe kwe-dihydrotestosterone, kukhona:

• hypogonadism emadodeni,
• i-benign prostatic hyperplasia,
• ukuphazamiseka kwifa lemvelo lokukhiqizwa kwama-alpha-rectase,
• I-Morris syndrome (ibonakala ngokuntuleka kokuqothuka kwe-androgens),
• ukuntuleka kwama-androgens, okucasulwa izinguquko ezihlobene nobudala - ezimweni ezinjalo, ukungakwazi ukuqina kwenzeka emadodeni, futhi i-libido iyancipha kwabesifazane.

Lapho kukhona i-benign prostatic hyperplasia, ukuhlaziya kwe-dihydrotestosterone kunikezwa ukuqapha isimo sesiguli nokulawula ushintsho lapho usebenzisa amayeza, aqukethe ama-5-alpha reductase inhibitors. Abesifazane ezimweni eziningi badlulisa ukuhlaziywa okunjalo ukuthola imbangela yokuvela kwe-hyperandrogenic dermopathy.

Ukwanda kwe-dihydrotestosterone emadodeni: izimbangela nokuthi wehla kanjani izinga

Ubuntu obukhona, isihluku sendoda, amandla omzimba - ukubaluleka kwe-hormone ekhiqizwa emzimbeni wesilisa (ikakhulukazi kuma-testicles) kusuka ku-testosterone lapho kuvezwa ukusabela kwe-enzymatic.

Le hormone yi-dihydrotestosterone, izinga lapho kwezinye izimo lingase lidlule amanani ajwayelekile.

I-DHT ibandakanyeka ekwakhekeni kohlobo lomthethosisekelo olujwayelekile lwesibalo sensizwa, ukuthuthukiswa kwezitho zobulili, indlala ye-prostate, ukwakheka kokukhula kwezinwele, ubulili kanye nezinga le-potency. Izicubu, izicubu namathambo emathambo asekelwa umsebenzi waleli hormone.

Iziphakamiso zokulungiselela ukuhlaziya

Ukuhlaziywa kokuqukethwe kwe-dihydrotestosterone kumele kuthathwe ekuseni, okungcono kakhulu phakathi kwamahora angama-8 no-11, esiswini esingenalutho. Ngaphambi kokuhlola, ungaphuza amanzi namanje. Kungcono ukwenqaba ukusetshenziswa kwetiye, ikofi, ushukela kanye namajusi. Ngobusuku bangaphambi kokuhlolwa, akunconywa ukuthi udle ukudla okunamafutha.

Izinsuku eziyi-1-2 ngaphambi kokuhlolwa kwegazi kokuqukethwe kwe-dihydrotestosterone, udinga ukwenqaba ukuphuza utshwala nogwayi, ungaphakamisi izinto ezisindayo, ungahlanganyeli nemidlalo esebenzayo. Kunconywa ukuthi uyeke ukuthatha lo muthi, kepha lokhu kufanele kuvunyelwane kuqala nodokotela.

Isigamu sehora ngaphambi kokuhlolwa kwegazi, isiguli sidinga ukwehlisa umoya, sithathe isimo esihle futhi siphumule. Izimo ezicindezelayo kanye nokukhandleka okungokomzwelo ngosuku olwandulela ukuhlaziywa kuyaphulwa.

Akunakwenzeka ukuthatha ukuhlolwa kwegazi kwe-dihydrotestosterone ngemuva kwezifundo ze-ultrasound kanye ne-x-ray, izinqubo zomzimba nezomzimba, njll.

Ukuhlolwa kokuqukethwe kwe-testosterone kunikezwa kaningana ngezikhathi ezithile ngezikhathi ezithile.

Ukuqapha imiphumela yokwelashwa, ukuhlaziywa ngakunye ngakunye kufanele kunikezwe ngaphansi kwezimo ezifanayo, endaweni eyodwa futhi ngasikhathi sinye.

Uma, ngesikhathi sokuhlolwa kwe-dihydrotestosterone, umuntu eyeka ukuthatha imishanguzo, kufanele wazise udokotela wakho ngalokhu, ngoba ezinye izidakamizwa zingahlanekezela imiphumela yokuhlaziywa.

Abesifazane bahlolwe kangcono i-dehydrotestosterone ekuqaleni komjikelezo wokuya esikhathini.

Kwelashwa kanjani?

Iqiniso lokuthi izinga le-DHT liphakanyisiwe linganqunywa kuphela ngudokotela ngemuva kokuhlolwa okuningiliziwe kwemiphumela yokuhlolwa. Ngokusekelwe emiphumeleni, kuzonikezwa ukwelashwa okufanele. Ezimweni eziningi, kunikezwa izidakamizwa ezahlukahlukene ze-hormonal. Imithi ethile kanye nesikhathi sokwelashwa kunqunywa udokotela.

Kumele kukhunjulwe ukuthi noma yikuphi ukungalingani kwe-hormonal kungaholela ezinkingeni ezinkulu zempilo. Ngokwenyuka kwezinga le-dihydrotestosterone egazini, ukwelashwa okunekhono nokwenziwa ngesikhathi kubalulekile. Ngakho-ke phendula kuzo zonke izinkomba zomzimba wakho futhi ungakulibazisi ukuvakashela esibhedlela. Inhlanhla futhi uphile!

Yabelana kuye nabangane futhi nakanjani bazokwabelana ngokuthile okujabulisayo futhi okuwusizo nawe! Kulula kakhulu futhi kushesha, kulula. chofoza Inkinobho yensizakalo oyisebenzisa kakhulu:

Imininingwane ejwayelekile nemisebenzi ye-dihydrotestosterone

I-Dihydrotestosterone yenziwa ngokuxhumana kwe-enzyme 5-alpha reductase (5-AP) ne-testosterone, ngenxa yalokho ama-athomu ama-2 e-hydrogen anezelwe kamuva (yingakho isiqalo "dihydro"). I-testosterone yamahhala ethe xaxa, yilapho ifomu layo elisebenza khona. Cishe i-70% ye-DHT yakhiwa emathanjeni wethambo. Ngokungafani ne-testosterone, i-dihydrotestosterone ibopha ama-androgen receptors izikhathi ezi-3-4 ngokwengeziwe ngenkuthalo, yakha inkimbinkimbi ezinzile nawo, eqinisekisa umphumela wayo omenyezelwe ekuhlushweni okuphansi (I-10% yezinga le-testosterone ejikeleza egazini). Umthamo oyinhloko we-DHT ugxiliwe ku-follicles yezinwele, esikhunjeni sendawo ye-inguinal, kanye ne-prostate. Izinga eliphakeme kakhulu lomsebenzi liboniswa ubuchopho, izitho zangasese kanye nesikhumba.

Imisebenzi esemqoka ye-dihydrotestosterone:

• Ama-receptor e-androgen asebenzayo atholakala ngamanani amakhulu kumaseli wezinzwa, ngakho-ke i-dihydrotestosterone inethonya elikhulu lokulawula ekusebenzeni kohlelo lwezinzwa oluphakathi,
• Iphakamisa ukuqina nokukhula kwezicubu zomzimba ngenxa yomthetho wezinzwa (i-testosterone inomphumela obalulwe ngokwengeziwe we-anabolic),
• Unomthwalo wemfanelo wohlobo lowesilisa, umsebenzi we-sebaceous gland, ukuthuthukiswa kwezitho zangasese,
• Kwandisa ukumelana kokucindezela okungokomzimba nangokwengqondo,
• Ilawula ikhwalithi ye-libido ne-erection.

Umsebenzi obalulekile we-dihydrotestosterone emzimbeni wesilisa ukuvikelwa kwe-estrogen. I-DHT ivimba umsebenzi we-aromatasengokubamba iqhaza kwalapho ama-androgen aguqulwa aba ngama-estrogens.Abesilisa abathatha ama-inhibitors we-5-AR bavame ukuqaphela ukubonakaliswa kwe-gynecomastia (ukuthuthukiswa kwesifuba) - umphumela wokuntuleka kwe-DHT.

I-Dihydrotestosterone emadodeni nayo ilawula umsebenzi wokuhlukaniswa kwamaseli wezicubu ze-prostate, ngakho-ke okweqile kwaleli hormone kuvame ukuholela kwi-hyperplasia ye-gland kanye nokuwohloka kwe-oncological.

Izimpawu nezimbangela zokuhlukunyezwa

Izinga elijwayelekile le-dihydrotestosterone (amanani ayisethenjwa) emadodeni amadala yi-250 - 990 pg / ml. Mayelana naleyo nkomba ngaphansi kokujwayelekileikhombisa izimpawu eziningana:

1. Ukuhamba kokuthomba kwentsha.
2. Ukwehliswa kwevolumu yemisipha, ukubekwa kwamafutha okhalweni nasiswini, ukukhuliswa kwesifuba.
3. Yehlisiwe i-libido, yakha ukwanda.
4. Ukuqedwa noma ukwehla kokukhula kwezinwele zomzimba.

I-Hypogonadism eyiPrayimari neSekondari Inokubangela amazinga aphansi we-Dihydrotestosterone - Ukuntuleka kwama-androjeni ngenxa yama-pathologies azalwe kabusha noma atholakele. Ezinye izinto:

• Ama-inhibitors ama-5-AR Abanye banokushoda okuzalwa kwalesi similo,
• I-Hypogonadism,
• I-Andropause (ukwehla okuhlobene nobudala bemvelo emazingeni e-testosterone).

Hhawu izinga eliphakeme Izimpawu ezilandelayo zibonisa i-dihydrotestosterone:

1. Ngaphambilini kuyimpandla. I-DHT eyeqile ibangela i-dystrophy yezicucu zezinwele, ngenxa yokuthi izinwele ziguqula umbala, ziba mncane, bese ziyawa. Ngaphezu kwalokho, i-whisky kanye emuva kwekhanda cishe akuhlupheki, ukulahleka kwezinwele kuqala ngebunzi nengxenye yephariyali. Umuzwa wamaseli we-bulb kuya ku-dihydrotestosterone unqunywa ngofuzo futhi udluliselwa ngomugqa womama (“gene baldness” - Sox21).
2. Isikhumba esinamafutha kakhulu, ukubukeka komqubuko ("I-Hormonal acne"). Ukunyuka kwe-dihydrotestosterone kucasula i-sebaceous gland (ngokuqondile, amaseli ayo - ama-sebocyte, ebusweni lapho kukhona ama-androgen receptors) ekukhiqizeni okunamandla kwe-sebum. Ngenxa yalokho, i-pore iyavalwa, ngaleyo ndlela idale indawo enhle yokuthuthuka kwamagciwane.
3. Ukuqina kwesikhumba.

Amadoda akhuphule i-dihydrotestosterone kaningi ahlukile ulaka olungenangqondo, ulaka, umlingiswa ongalingani.

Okuvuselelayo Izici ze-dihydrotestosterone ephezulu yilezi:

• Umuthi weSteroid
• I-Morris Syndrome (ukuntuleka kokuphendula kwezimpendulo kuma-androgens),
• Ama-tumors we-adrenal gland kanye nama-testicles,
• I-Hypergonadism
• Prostate adenoma.

Uma kunezimpawu ezibonisa ukungalingani kwe-dihydrotestosterone, kufanele uthintane nodokotela oyi-urologist, andrologist noma udokotela ojwayelekile.

Ukuxilonga

Ukucaciswa kwezinga le-dihydrotestosterone kwenziwa nge-enzymosorbenz assay ye-enzyme ye-venous yegazi (ELISA). Izindleko zocwaningo zincike esimweni sesikhungo sezokwelapha nendawo yaso okuyo. Isilinganiso intengo ingu-1300 p. Umphumela wokuhlaziywa kwe-dihydrotestosterone ungatholakala ngemuva kwezinsuku ezingama-7-9.

Izinkomba zokutholwa yilezi:

1. Ukusolwa kwe-adenoma noma isidingo sokulawula isimo se-prostate gland ngesikhathi sokwelashwa kwe-hyperplasia.
2. I-Alopecia (impandla).
3. Izimpawu zokuntuleka noma ngokweqile kwama-androgens.

Imithetho yokulungiselela ukuhlaziya:

1. Emahoreni ayisishiyagalombili ngaphambi kokuthatha isampula legazi, ungaphuza kuphela amanzi angenawo amakhabhoni, ukumuncwa kokudla nezinye iziphuzo ngaphandle.
2. Isigamu sehora ngaphambi kokuhlaziywa, akufanele ukhathazeke ngokomoya nangokomzimba nangokubhema.
3. Khipha utshwala neziphuzo ze-caffeine ngosuku.

Kubalulekile ukutshela udokotela wakho ngokuthatha ama-testosterone noma ama-5-alpha-reductase inhibitors. Ngobumsulwa bomphumela, ukwelashwa okuyiqiniso nalawa ma-ejenti kungaphazamiseka.

Uma i-dihydrotestosterone iphambuka kokujwayelekile, kubhekwa izivivinyo ezingeziwe: i-ultrasound yezitho zomzimba, i-Prostate, ama-testicles.

Amasu okuphatha anqunywa yimiphumela yokuxilongwa, ubudala besiguli kanye nokuba khona kwe-concomitant pathologies.

Kwenzekani ngokulinganisela nokungalingani

Ngesilinganiso esanele se-DHT, indoda iziphatha ngokuzethemba, ikhule kahle emzimbeni, umzimba uqinisiwe, izicubu zemisipha zakhiwa ngokujwayelekile. Amafutha amaningi awakhiwa.

Uma i-hormone inganele, khona-ke amadoda anezinga eliphansi lesifiso sobulili. Ukunyuka kwe-dihydrotestosterone kwethula ukungahambisani nokulinganisela kwe-hormonal, okuphoqa ama-receptors azwele ebukhoneni bawo ukuze aphendule.

Futhi njengoba igxiliswe ikakhulukazi kwizikhwanyana zezinwele nasekhunjeni lezitho zangasese, ukungalingani kwe-dihydrotestosterone emzimbeni endodeni kubonakaliswa ukulahleka kwezinwele, kwesinye isikhathi isifo sikashukela nezifo zeprostate, lapho kwakhiwa amathumba (kufinyelela kumdlavuza we-Prostate).

Izimo zokucindezelwa zivame ukuchazwa ngokweqile okukhona unomphela kwe-dihydrotestosterone, indoda ebingazi ngayo.

Izici zezwe

Izinqubo zomzimba noma izifo lapho i-dihydrotestosterone iphakanyisiwe:

• Ukwelashwa ngemishanguzo ye-hormonal, kufaka phakathi izinga le-dihydrotestosterone ye-hormone.
• Izici zofuzo, njenge-hypergonadism.
• I-Prostate adenoma emadodeni.
• I-Microadenoma yobuchopho (i-pituitary gland).
• Izinqubo ze-tumor zezindlala zangasese.
• IHepatoplastoma.
• Ukusebenza kwesibindi okunganele noma izinqubo zesimila ku-adrenal gust.

Uma kwabesifazane ukuqaqa ku-DHT kungabangelwa umthamo wePostinor, khona-ke kwabesilisa isimo sibi kakhulu.

Izimpawu zangaphandle ezibonakalayo azinabungozi - ukungalingani, lapho i-dihydrotestosterone ikhuphuka noma incipha, ingaba isibuko sezehlakalo ezenzeka emuva komzimba, kwesinye isikhathi kube nengozi empilweni.

Ukuvimbela ukukhula kwezifo ezinkulu, qaphela noma yiziphi izibonakaliso zokungahambi kahle lapho ziqala ukuvela kuphela. Isifo esitholwa yisikhathi selashwa kalula futhi sishesha ukwedlula ngenkathi sasungulwa.

Ukwanda kwehomoni kungabonakala nge-adenoma yasesikhathini.

Kodwa i-dihydrotestosterone iphakanyisiwe emadodeni hhayi njalo maqondana nokugula okungathi sína. Kwesinye isikhathi ukuphambuka kusuka kokujwayelekile kuqoshwa lapho isiguli sithola ukwelashwa ngama-5-alpha-reductase inhibitors (inani laso lixhumene nokukhiqizwa kwe-DHT).

Uma kutholakala ukuthi izinga le-dihydrotestosterone liphakanyisiwe, kanye nezizathu ezalithonya, kuyadingeka ukuthi uqale ngokushesha ukwelashwa futhi wehlise inkomba.

Kuyadingeka ukwehlisa inani kuya kokujwayelekile kwesilisa kwaleli hormone, okunomehluko ngokweminyaka.

Imvelo ye-dihydrotestosterone yamadoda isezingeni elibanzi le-25-990 pg / ml, kucatshangelwa ama-nuances aqondakalayo kuphela, ngakho-ke kunconyelwa kakhulu ukuthi ungazithobi ngokwakho.

Thintana nomtholampilo lapho uhlala khona - lokhu kuzosheshisa ukutholwa kwakho futhi kukuvikele ekwandeni kwezinqubo ze-pathological.

Inkinga yokuxazulula inkinga

Ezokwelapha azifundanga ukuthi zingakuvimbela kanjani ukwenzeka kokuphazamiseka kwe-hormonal, kepha ukwelashwa okufika ngesikhathi kungasishintsha ngokushesha isimo sesiguli.

Yimuphi udokotela okufanele ngiye kuye? Ngokuqukethwe okuphezulu kwe-dihydrotestosterone emadodeni, izincomo zinikezwa ochwepheshe - udokotela oyi-urologist kanye ne-endocrinologist.

Ungawehlisela kanjani izinga le-DHT, ikakhulu kuya ngembangela yokwanda kwayo, izici zesithombe somtholampilo kanye nesimo sezinye izitho emzimbeni wesiguli.

Uhlobo lokwelashwa luhlala lungamuntu ngamunye, ngoba izinqubo ze-endocrine zintekenteke futhi ziyaxhuma. Udokotela we-endocrinologist onolwazi kuphela onganquma yonke inkimbinkimbi yemininingwane exhunyiwe, futhi uzokhetha ukwelashwa.

Imvamisa bekwenzelwa ukuqokwa kwezidakamizwa zama-hormonal ezinaka ukuguquguquka okucashile kokungalingani kwamahomoni eguli uqobo.

Ngokungafani nabesifazane, okuthi kubo kulezi zimo kunekhambi elilodwa kuphela - iDiane 35, iziguli zesilisa ziphathwa ngokuphelele, zisebenzisa izinkomba ezahlukahlukene zokwelapha.

Ngokwanda kwe-hormone, kunconywa ukuxhumana nodokotela oyi-urologist noma i-endocrinologist.

Ngenye indlela, amadoda anamazinga aphezulu we-DHT angahle abekelwe ama-inhibitors (ama-suppressants) we-5-alpha reductase. Phakathi kwabo kukhona iBuserelin, Deslorelin. Basiza ukunciphisa i-dihydrotestosterone. Eminye imithi engenzeka yiMedroxyprogesterone, Spironolactone. Ketonazole Kepha konke ukuqokwa kumele kwenziwe kuphela ngudokotela ohambelayo.

Khumbula ingozi yokulimaza impilo yakho ngemithi yokuzelapha engaphezulu kwesifo esivele ikhona.

Njengomuthi wemvelo, ungasebenzisa izitshalo ze-antiandrogenic zokwelapha ezinciphisa ukukhiqizwa kanye nokwakheka kwe-DHT:

• Imbewu yethanga netiye eliluhlaza.
• Amafutha efilakisi ne-stevia.
• Amavithamini C, B6 futhi afakwe umlilo.
• Ubisi thistle kanye fenugreek.

Uma isithombe saleso sifo senezelwa ukukhuluphala, ukudla okuqukethe inani eliphansi lama-carbohydrate kufakwa ekwakhiweni kwezidakamizwa zokwelapha. Kwesinye isikhathi ngisho nalesi silinganiso esincanyana sinomthelela esivivaneni sokwenza kube ngokwejwayelekile ukulingana kwehomoni.

I-Mensgen.ru »Ama-Hormones» Kungani kunokwanda kwe-dihydrotestosterone nokuthi ungayinciphisa kanjani emzimbeni wesilisa

I-Dihydrotestosterone emadodeni: imisebenzi, izinga elijwayelekile kanye nokuphambuka

I-Dihydrotestosterone emadodeni yi-hormone ekhiqizwa kusuka ku-testosterone ngokusabela kwe-enzymatic. Kukhona ezinye umehluko phakathi kwe-testosterone nedihydrotestosteroneokuthinta ukusebenza kwama-hormone emzimbeni. I-DTG ilawula ukusebenza okujwayelekile kwendlala yesibeletho nazo zonke izitho zohlelo lwezitho zofuzo.

I-Dihydrotestosterone onesibopho sokubukeka okufika ngesikhathi kwezimpawu zesibili zobudoda emadodeni kanye nobudala, ukuqina kwayo emzimbeni kungashintsha.

Ukuphambuka kwezinga lama-hormone kusuka kokujwayelekile kungakhombisa ama-pathologies ahlukahlukene, ngakho-ke kubalulekile ukuthi njalo wenze izifundo futhi ubheke amazinga e-DHT egazini.

Thola dihydrotestosterone — inikunjalo nokuthi kubaluleke ngani kowesilisa, ungaya ku-urologist.

Imisebenzi ye-Dihydrotestosterone

Uyini umehluko testosterone kusuka ku-dihydrotestosterone, futhi imiphi imisebenzi eyenziwa ama-hormone anjalo emzimbeni? I-Dihydrotestosterone yi i-hormone ekhiqizwa emadodeni.

Uma kuqhathaniswa ne-testosterone, ixhumana kakhulu nama-receptor amaselula, ngakho-ke umsebenzi wayo we-androgenic ubonakala kakhulu.

Into enjalo inomthelela obalulekile ekuthuthukiseni nasekusebenzeni kwe-prostate ngokuzayo, ngakho-ke, kwezokwelapha isetshenziswa kabanzi ukuqeda izifo ze-prostate.

Esimweni lapho ukuqoqwa kwe-dihydrotestosterone emzimbeni wesilisa kukhuphuka kakhulu futhi kudlule izinkambiso ezivumelekile, khona-ke kukhona ukwanda okuphawuleka ngosayizi weprostate. Ngaphezu kwalokho, ama-pathologies ahlukahlukene aqala ukuthuthuka futhi ukwakheka okunjenge-tumor ezicutshini zeprostate kuyatholakala.

Ukuqoqwa kwe-dihydrotestosterone kunqunywa ukukhiqizwa nokuqukethwe kwe-testosterone emzimbeni wesilisa. Okukhudlwana kokuqukethwe kwalokhu okugcina, inani layo likhula kakhulu ku-DHT. Kuyadingeka ukugcina izinga elijwayelekile le-hormone enjalo ngenxa yokulawulwa kwe-testosterone, ukukhiqizwa kwayo kulawulwa yi-hypothalamus kanye ne-pituitary gland.

I-Dihydrotestosterone ibamba iqhaza kakhulu ekuthuthukiseni nasekusebenzeni kwezinye izitho, futhi inomphumela oqondile ezinqubweni zemvelo nezezifo. I-hormone enjalo ilawula isimo sezitho zangasese, izicubu zemisipha, izinhlamvu zezinwele nohlelo lwamathambo.

I-DHT inomphumela omuhle ekukhuleni ngokomzimba ebusheni hhayi kuphela esicini sezimpawu zesibili. I-hormone enjalo isiza ukusheshisa ukwakheka kwezicubu zemisipha kanye nokubola kwamafutha. I-DHT ithinta isenzo sobulili sendoda, ngakho-ke ukuntuleka kwayo komzimba kuba ngesinye sezimbangela zokungabi namandla futhi kunciphe i-libido.

Izimpawu zokuphambuka

Isibonakaliso sokuqala kakhulu esibonisa lokho ukukhuphuka kwe-dihydrotestosterone emadodeni, ukuthola izinkinga zezinwele.

Ngamanye amazwi, izinwele ziwela ngaphandle, ukukhula kwazo kuncipha futhi ngokuhamba kwesikhathi indoda iba yimpandla.

I-hormone enjalo emzimbeni wesilisa ibuye ithinte ezinye izicubu nezitho zomzimba, ngakho-ke, ukwephulwa kokuqukethwe kwayo kuhambisana nokubonakala kwezimpawu ezithile.

Ukushoda kwe-Hormone kubafana kubangela ukungasebenzi kahle kakhulu ekuthuthukiseni ezocansi. Ezinganeni ezinjalo, izinwele azibonakali emaphethweni nakwezinye izingxenye zomzimba, futhi kukhona nokuhlukumezeka ekwakhekeni kwepenisi. Ngaphezu kwalokho, kunokuntuleka okubonakalayo kwesisindo semisipha, futhi ipenisi noma amasende ancishiswe kakhulu ngosayizi.

Esimweni lapho dihydrotestosterone emadodenikwehlisiwe, lapho-ke kungavela ubufazi, ukungafani kwemilenze kanye nobunzima besibalo.

Imvamisa, iziguli ezinje ziphawuleka phakathi kwabantu abanemvelo ebulalayo futhi enobuthi, futhi bavalekile kakhulu ngaphakathi.

Ukuntuleka kwe-DHT emadodeni kuholela ekwehleni kwesifiso sobulili kanye ne-potency engasebenzi kahle ezinkingeni nge-erection.

Esimweni lapho dihydrotestosterone ephakanyisiwe emadodeni, khona-ke akukho lutho oluhle kulokhu nalo lulandelayo. Ezintweni zamadoda, kunokungalingani okukhanyayo kwama-hormone, ukukhula kwezinwele ekhanda kuyayeka futhi izimpandla ezisebenzayo ziyabonakala.

Khulisa amazinga e-dihydrotestosterone emadodeni noma nge-pg / ml embalwa, ihambisana nentsha ende ngokweqile, ukwakhiwa okungapheli komzimba wakhe nesikhumba esinyayo

I-Dihydrotestosterone nomzimba wesifazane

Ukuqonda indima ye-dihydrosterone emzimbeni womuntu wesifazane, kuyadingeka ukuqonda ukuthi yini nokuthi yakheka kanjani.

Uzokhohlwa ngesifo se-thyroid uma uphuza ingilazi engu-1 ekuseni.

I-Dihydrotestosterone - Le yi-hormone yabesilisa, yona kanye nama-hormone abesifazane, elawulwa yigazi. I-Androgen, i.e.horms yabesilisa, ifikelwa imfihlo i-adrenal cortex ne-ovarian ingxenye. Kwakhiwa kusuka ku-testosterone (i-hormone yobulili yabesilisa) ngokubamba iqhaza kwe-enzyme ekhethekile, isakhi samaprotheni - 5-alpha reductase.

I-Dihydrotestosterone inethonya elinamandla kune-testosterone futhi ibaluleke kakhulu emzimbeni wesifazane.

Indima ye-DHT emzimbeni wowesifazane:

• Ihlanganyela emsebenzini wezindlala ze-sebaceous kanye nomthethonqubo wokujuluka,
• obhekele ukukhula kwezinwele, izicubu kanye nethambo lowesifazane,
• ilawula i-libido yabesifazane,
• Kuyingxenye ebalulekile yamafutha, amaprotheni kanye ne-carbohydrate metabolism emzimbeni.

Isimo se-dihydrotestosterone kwabesifazane nabesilisa

Ukuthola noma yikuphi ukuphambuka ekukhiqizeni kwe-dihydrotestosterone emzimbeni wowesifazane noma owesilisa, ochwepheshe basebenzisa izinkomba ezijwayelekile. Ukuqoqwa kwe-dihydrosterone emzimbeni wesifazane kunqunywa kusetshenziswa ukuhlolwa kwegazi lomtholampilo, khona-ke izinkomba ziqhathaniswa nokujwayelekile.

Ithebula lezinkomba zesibonakaliso se-dihydrotestosterone emadodeni nakwabesifazane ngeminyaka:

Kwabesifazane bobudala bokuzala, inani le-dihydrotestoster libhekwa njengesiwombe esingaphakathi 24-250 pg / mlnokho, esikhathini se-postmenopausal, le nkomba incishisiwe. Umsebenzi ophakeme we-dihydrotestosterone emzimbeni wenzeka ngqo esikhathini sokuguqulwa kwentsha, lapho ukuthomba kwenzeka. Kulesi sigaba, izinga le-dihydrotestosterone esegazini libaluleke kakhulu, ngoba le androgen inesibopho sokuthuthuka okuvumelanayo komzimba.

Ukunyuka kwamazinga e-Dihydrotestosterone

Ngokusebenza okujwayelekile kwezitho zangasese nazo zonke izinhlelo zomzimba, ibhalansi yama-owesilisa nowesifazane inomthwalo wemfanelo. Uma izinga le-hormone dihydrotestosterone emzimbeni wowesifazane noma wentombazane landa, khona-ke izinhlelo eziningi ziyehluleka. Isibonelo, ebusheni, amantombazane akhombisa izimpawu zokuqala zokwanda kwe-dihydrotestosterone emzimbeni:

• induna yobusha, induna,
• umjikelezo wokuya esikhathini ngokungajwayelekile noma ukungabikho kwawo ngokuphelele,
• amathambo wesilisa ayakhula,
• kwakheka iphimbo elinamandla.

Lezi zinto aziwona ukuphambuka kokujwayelekile, noma kunjalo, uma umjikelezo ungalulami ngemuva kweminyaka emibili, khona-ke lokhu kungaba wuphawu lokukhula kwe-dihydrotestosterone.

Ukuphazamiseka kweHormonal kwe-dihydrotestosterone kuvame ukwenzeka lapho umuntu umdala.

AtAbesifazane abane-dihydrotestosterone ephakeme bathola lezi zimpawu ezilandelayo:

• ukukhula kwezinwele emzimbeni, ikakhulukazi ebusweni, ngaphezulu komlomo omkhulu, kuyathuthukiswa
• umjuluko uyanda
• izinwele ziwe
• isisindo somzimba siyakhuphuka
• ukukhula kwesifiso sobulili,
• usayizi we-clitoris ne-labia uyanda
• isikhumba esinenkinga yamafutha.

Kubalulekile! Ukuvela kwenye yalezi zimpawu kungenzeka kungakhombisi ukukhuphuka kwe-dihydrotestosterone egazini, kepha kungenye yezizathu zokuya kudokotela.

Kwabesilisa, izimpawu eziphambili ze-dihydrotestosterone eyandayo ukulahleka kwezinwele nokuziphatha okunolaka, ngenxa yokuthuthuka kwe-adenoma noma ukuzala kokuzala. Ngokuqondene nomzimba wesifazane, keizizathu zokwanda kwe-dihydrotestosterone egazini libonisa ubukhona bama-pathologies alandelayo:

• Androgenic adrenal tumor,
• ukuphazamiseka kwe-metabolic emzimbeni wowesifazane,
• i-ovary polycystic,
• ukungazali
• isifo sikashukela mellitus
• ushintsho lokuzalwa noma lokutholwa kwe-pathological ku-hypothalamus (ingxenye ye-diencephalon, ebhekele ukusebenza kwezinhlelo eziningi emzimbeni, kufaka phakathi i-adrenal gland).

Yehlise i-dihydrotestosterone

Futhi kwenzeka ukuthi i-hormone dihydrotestosterone ikhiqizwa kabi kwabesifazane, izinga layo liphansi kakhulu kunokujwayelekile.

Amazinga we-Dihydrotestosterone ancipha ngenxa yezizathu eziningana:

• ukuntuleka kwe-androgen
• I-Morris syndrome (ukuphazamiseka kwemizwa ekuthuthukisweni kobulili).
• isifo sikashukela mellitus.

Ukwehla kwamazinga e-testosterone ne-dihydrotestosterone kunganqunywa ngezimpawu zangaphandle. Isibonelo, emadodeni anokwehla kwe-dihydrotestosterone, ukuncipha kwezinwele, ukwehla kwesisindo semisipha, ukuthuthukiswa okungafani kwezitho zomzimba kanye nokukhuluphala kohlobo lowesifazane kuyaqala.

Ngokuqondene nabesifazane, izinga elincishisiwe le-dihydrotestosterone libonakaliswa yizici ezilandelayo:

• wehlise kakhulu isifiso sobulili,
• ukuqwasha, ukukhathala,
• isikhumba esomile.

Kubalulekile! Uchwepheshe kuphela ozokwazi ukuthola imbangela yangempela yokuvela kwezimpawu ezinjalo ngokuhlola imiphumela yokuhlonza ukuthola inani le-dihydrotestosterone egazini lowesifazane. Mhlawumbe ukungalingani kwe-dihydrosterone akuqinisekisiwe.

Ilungiselela ukuhlolwa

Uma uye kudokotela nezimpawu ezichazwe, khona-ke uzokuqondisa ukuthi uhlaziye ukuze kutholakale izinga le-dihydrotestosterone esegazini.

Ukuze kuhlaziywe izinga le-dihydrotestosterone ukukhombisa imiphumela efanele kakhulu, kuyadingeka ukuyilungiselela ngokufanele:

1. Ukuhlaziywa kokunqunywa kwezinga le-dihydrotestosterone kwabesifazane kwenziwa kangcono esiswini esingenalutho. Uma ungeke ukwazi ukwenza ngaphandle kokudla, umuntu uvunyelwe ukuthi aphuze itiye noma asamanzi. Ukudla kwakusihlwa ngosuku olwandulela isifundo kufanele kube lula, kube namafutha amancane kanye namakhalori amancane.
2. Ezinsukwini ezintathu ngaphambi kokuhlaziywa kwezinga le-dihydrotestosterone egazini, kuyadingeka ukushiya utshwala, ukubhema nemithi enamandla.
3. Gwema izimo ezicindezelayo.
4. Ukuhlaziywa kunganikeza imiphumela engalungile uma ngosuku lwesiguli kwenziwe i-ultrasound, i-x-ray, i-MRI noma i-massage.
5. Qinisekisa ukwazisa uchwepheshe ngokuthatha imishanguzo, inkambo ongenalo ilungelo lokukuphazamisa.

Ukuthatha nini abesifazaneUkuhlaziywa kungcono kakhulu uma kungokweminyaka yokuzala? Lapho uhlola izinga le-dihydrotestosterone esegazini, kufanele kubhekwe ukuthi uluphi usuku lomjikelezo owela ngalo wesifazane kulolu suku.

Inqubo yenziwa ngokukhethekile ezinsukwini ezingama-2-4 ngemuva kokuqala kokuya esikhathini. Njengoba izinga lamahomoni ahlotshaniswa nomsebenzi wokuzala lingahluka ngokuya ngezigaba zomjikelezo wokuya esikhathini.

Izindlela zokwelapha

Noma yikuphi ukwephulwa kwesizinda se-hormonal kowesifazane kudinga ukwelashwa okuhleliwe, okuzonciphisa noma kukhuphule izinga le-dihydrotestosterone. Kodwa-ke, kunezimbangela ezingezona ze-pathological zezinga eliphakeme noma eliphansi le-dihydrotestosterone kwabesifazane.

Kulesi simo, ukuqeda lezi zinkinga, kuthatha isikhathi (isikhathi sobusha) nokubonisana njalo nodokotela ozobonakalisa ukubonakaliswa kwezimpawu zangaphandle zokushintshwa kwe-dihydrotestosterone futhi uzokwazi ukuqala ukwelashwa okufika ngesikhathi uma kunokungalingani isikhathi eside.

I-Dihydrotestosterone dysfunction yenzeka ngesikhathi sokukhulelwa, ukuya esikhathini noma izidakamizwa ezithile IGoserelin, iDanazol, iPhenytoin nezinye izidakamizwa. Udokotela ukhetha izidakamizwa ngazinye esigulini ngasinye futhi kuya ngembangela yokungahlali kahle kwe-dihydrotestosterone emzimbeni wowesifazane.

I-Dihydrotestosterone kanye nokulahleka kwezinwele kuyaxhunyaniswa, ngoba ukukhiqizwa kwenhlanganisela yamaprotheni kuncike ekusebenzeni kwezikhwanyana zezinwele. Ngakho-ke, owesifazane uqala ukuba nomzimba omncane futhi izinwele ziwe ngaphandle. Ungawehlisa kanjani izinga le-dihydrotestosterone kuleli cala? Ukunciphisa i-androgen kwabesifazane, kunqunywe izidakamizwa ezikhethekile - ama-blocker 5-alpha reductase.

Okuvame kakhuluizidakamizwa ezinciphisa izinga le-dihydrotestosterone emzimbeni wowesifazane yilezi:

Ama-phytoestrogens (phytohormones akhiqizwa ezitshalweni) asiza ukunciphisa ukukhiqizwa kwe-dihydrotestosterone: izithelo zesundu emfushane, i-clover ebomvu, u-soy, i-alfalfa, iminti, i-chamomile, i-sage.

I-Nettle , njengenye yezinhlobo zama-phytoestrogens, onomphumela omuhle ekunciphiseni izinga le-dihydrotestosterone kwabesifazane. Izindlela zokuvimbela inzalo zomlomo ziyasebenza futhi ekwelapheni ukuvalwa kwesilinganiso se-DHT emzimbeni womuntu wesifazane: U-Yarina, uJanine, uDiane-35.

Kubalulekile! Imithi enciphisa izinga le-dihydrotestosterone kowesifazane inomphumela omfushane, okungukuthi, ngesikhathi sokuphatha kwabo.

Nge-polycystosis, uma owesifazane ehlela ukukhulelwa, udokotela oholayo angakunikeza izifakelo ze-ovulation esigulini - izixazululo ze-intramuscular (Puregon, Menogon) noma amaphilisi Klostilbegit.

Uma izinga le-dihydrotestosterone lowesifazane likhuphuka ngenxa yokunganakwa kwezithako ezithinta izicubu ku-glucose, lapho-ke ukudla okune-carb ephansi kuyokwanela ukwehlisa isisindo. Ngokuhamba kwesikhathi, ibhalansi ye-hormonal izolulama kancane kancane ngaphandle kokusetshenziswa kwemithi futhi izinga lokukhiqizwa kwe-dihydrotestosterone libuyele kokujwayelekile.

Nge-testosterone ephansi, udokotela uvame ukunquma imishanguzo ye-hormonal ezosiza ukubuyisa nokugcinwa komzimba kowesifazane.

Kwezinye izimo, ama-pathologies awalapheki, lapho kwenzeka ukuthi izinga le-dihydrotestosterone kumele ligadwe njalo yimithi.

Isiphetho

Abesifazane abaningi bazama ukwelapha ukulahleka kwezinwele ngemithi yesintu, amavithamini kanye nezinqubo ezahlukahlukene zokugcoba, ngaphandle kokusola izinkinga ezinkulu ngokwenziwa kwe-dihydrosterone. Kodwa-ke, ukwelashwa okubonakalayo akuvezi imiphumela yesikhathi eside.

Udokotela-endocrinologist kuphela ongakwazi ukuxilonga futhi anikeze usizo olufanele ngokungalingani kwe-hormonal kwe-dihydrotestosterone kwabesifazane. Musa ukuzindla futhi ungayinaki impilo yakho!

I-DHT isebenza kwabesifazane nabesilisa

Imisebenzi eyinhloko ye-DHT emzimbeni wesilisa ihlotshaniswa nokwakhiwa kanye nokukhula kohlelo lokuzala nezimpawu zobulili. I-Dihydrotestosterone emadodeni inomphumela olandelayo:

• ivuselela i-spermatogenesis,
• kuvimbela imfihlo yokuqunjelwa kwe-luteinizing hormone emthambekeni wezinto ezingaphandle,
• kuthinta ukusebenza kokusebenza kwamaseli we-gonadotropic ku-adenohypophysis,
• ivusa ukukhula kwendlala yesitho sangasese sangaphansi kanye nezitho zangasese zangaphandle esikhathini sokukhulelwa, ikhuthaza ukukhula kwabo ebusheni,
• yakha izici zobulili zesibili,
• ilawula ukwakheka kanye nentuthuko yohlelo lwamathambo, ukukhula kwemisipha,
• kunomthelela ovuselelayo kuhlelo lwezinzwa,
• ilawula i-libido
• obhekele ukwenziwa kwe-sebum,
• kuthinta izinhlamvu zezinwele, inesibopho sokukhula kwezinwele zocansi.

I-DHT nayo ikhiqizwa emzimbeni wesifazane. Umthombo oyinhloko wokukhiqizwa kwe-dihydrotestosterone kwabesifazane yi-adrenal cortex, amaseli we-ovarian, kanye nokuguqulwa okuvela kuma-steroid e-hormone angaphambi kwesibindi, izicubu, isikhumba nezicubu ze-adipose.

Imisebenzi ye-DHT emzimbeni wesifazane:

• kuthinta i-carbohydrate, amaprotheni, umzimba-okunamafutha amaningi,
• inquma ukuthuthukiswa kwamathambo nemisipha yamathambo,
• ilawula ukujuluka,
• kusebenze izindlala ze-sebaceous,
• yakha i-libido.

Ukwanda okubaluleke kakhulu kuzinga le-dihydrotestosterone kubonwa esikhathini sobusha, inani eliphakeme lokukhiqizwa kwalo liwela eminyakeni engama-25. Ngokukhula kweminyaka, ukukhululeka kwe-hormone kuyancipha kancane kancane.

Endabeni yokuphazamiseka kokusebenza, kungenzeka ukwenze kube ngokwejwayelekile ukulinganisela kwe-hormonal ngaphandle kokungenelela kwezokwelashwa ngosizo lokulungiswa kwendlela yokuphila.

• kufika eminyakeni eyi-10: 5-25 pg / ml emantombazaneni no-5-50 pg / ml kubafana,
• kusuka eminyakeni eyi-10 kuye kweli-12: 24-450 pg / ml emantombazaneni, ama-5-50 pg / ml kubafana,
• kusuka eminyakeni engu-13 kuye kweli-18: I-24-450 pg / ml emantombazaneni kanye ne-250-700 pg / ml kubafana,
• kusuka eminyakeni engu-18 kuye kwengama-50: 24-450 pg / ml kwabesifazane kanye ne-250-990 pg / ml emadodeni,
• kusuka eminyakeni engama-50: I-10-181 pg / ml kwabesifazane, 250-700 pg / ml emadodeni.

Ukuphambuka ekusithekeni kwe-DHT kungaholela ekwephulweni okukhulu komsebenzi wezinhlelo ezihlukene zomzimba.

Yehlisiwe i-DHT

Imvamisa, izinga eliphansi le-hormone libonakala emadodeni emva kweminyaka engama-30 kuya kwengama-40.

Izimbangela zokuncipha kwamazinga e-DHT emadodeni

• ukukhuluphala
• isifo sikashukela mellitus
• Ukuntula kwe-alpha reductase
• ukuntuleka kwe-androgen
• i-hypogonadism (ukungapheleli kwezitho zangasese).
• i-prostatitis engapheli
• I-Morris syndrome (testicular feminization syndrome).

Izimpawu zokuncipha kwamazinga e-DHT emadodeni:

• amadiphozi abesifazane (amathanga, amabhuzu),
• ukubambezela ukuthuthukiswa kwezocansi ebusheni, ukukhula okungafani namalungu,
• ukuthuthukiswa kwesibalo ngokuya ngobunikazi besifazane,
• usayizi wethambo elehlisiwe, isakhiwo saso esingajwayelekile,
• ukukhula kancane kwezinwele ebusweni, ebuhlungwini, emithini,
• ukudana, ukubekeka ngokomzwelo,
• ukukhathala,
• ukuntuleka kwesisindo semisipha
• ukungabi namandla, idrayivu yokuncipha ehlile,
• ukungasebenzi kahle kokuzala, izinguquko ku-spermogram.

Ama-pathologies we-pituitary gland, ama-ovari, izindlala ze-adrenal, izifo ezihambisana nokushoda kwezicubu ze-adipose zingaholela ekukhuleni kokuntuleka kwe-androgen kwabesifazane. Ukushoda kwe-DHT kwabesifazane kubonakaliswa ukwehla kwesisindo semisipha, imizwa yokuxineka, ukuthambekela kokudangala, ukwehla kwe-libido, kanye nokwehla kwezwi lesikhumba nobukhulu.

Lapho i-dihydrotestosterone iphakanyisiwe

Amazinga aphakeme we-dihydrotestosterone emadodeni angakhombisa ukuphazamiseka okulandelayo:

• i-adrenal gland tumor
• isimila sangasese,
• ukuvuvukala okulimazayo nokulimazayo kokulimala kwendlala,
• I-hypergonadism (ukusebenza ngokweqile kwama-gonads),
• isifo senhliziyo.

I-DHT eyeqile nayo ingadalwa ngokuthatha imishanguzo equkethe ama-androgens.

Imisebenzi eyinhloko ye-DHT emzimbeni wesilisa ihlotshaniswa nokwakhiwa kanye nokukhula kohlelo lokuzala nezimpawu zobulili.

Izimpawu zokwanda kwe-DHT emadodeni:

Izimbangela ezingaba khona zamazinga okunyuka kwama-hormone kwabesifazane:

• isimila se-adrenal,
• isifo sikashukela mellitus
• isimila esikhiqiza i-androgen emithanjeni ye-adrenal noma kuma-ovari,
• ukungondleki, ukukhuluphala,
• i-pathology ye-hypothalamus,
• ukuthatha izidakamizwa ze-hormonal.

Ukwanda ngokomzimba noma ukwehla kwe-DHT kuyabonakala ngesikhathi sokuthomba, kwabesifazane ngaphambi kokukhulelwa nangemva kokukhulelwa, ngesikhathi sokukhulelwa nokuncelisa.

Uma i-DHT iphakanyisiwe, lokhu kungakhipha ama-pathologies amaningi.Amazinga aphezulu we-DHT kwabesifazane abonakala ngezimpawu ezilandelayo:

• i-hirsutism
• fiphaza ukuthamba kwekhanda,
• ukujuluka ngokweqile
• ukuqina kwezwi
• induna, seborrhea,
• ukuthuthukiswa kwesikhumba sohlobo lwamadoda,
• ukukhuluphala
• I-hypertrophy ye-clitoris ne-labia,
• ukwehluleka kokuya esikhathini
• ukungazali

Umqondo wama-hormone nezenzo zawo

Ngaphambi kokuthola ukuthi ziyini izizathu zokwanda kwe-dihydrotestosterone nokuthi yini ongayenza ngayo, kufanele ukhumbule inkambo yesikole ye-anatomy. Ngakho-ke, ama-androgens anqoba emzimbeni wamadoda.

Kunezinhlobo ezi-5 zama-androgens sezizonke. Ngaphezu kwalokho, izinhlobo ezingama-2 ze-androgen kuphela ezinomphumela oqondile ekwakhekeni kwamadoda. I-Dihydrotestosterone yi-hormone enomphumela owethulwe kakhulu kuma-receptors.

Le hormone inomthwalo wemisebenzi eminingana:

1. Ukukhula komzimba womuntu. Eqinisweni, i-DHT ibhekele izinqubo eziningi ze-anabolic. Ngokuqukethwe okwanele kwaleli hormone egazini, indoda igcina isibalo esingokwemvelo, okungukuthi, amahlombe abanzi, okhalweni olubanzi nezinkalo. I-Dihydrotestosterone nayo inesibopho sokwakha izicubu zomzimba futhi inesandla ekushisweni kwamafutha angaphansi kwe-subcutaneous.
2. Ukuziphatha ngocansi. Ngokuqukethwe okwanele kwe-DHT, indoda igcina ukwakhiwa okuhle kanye ne-libido ephezulu. Uma izinga le-hormone likhuphuka noma liwa, khona-ke ukwehluleka okuhlukahlukene kuyabonakala.
3. Ukuba khona kwezimpawu zobulili zesibili. Ama-hormone ocansi ajwayele ukusiza ukugcina izwi eliphansi, ukubukeka kwezinwele esifubeni nasesiswini. Iqiniso elithandekayo ukuthi ukwanda kwe-dihydrotestosterone endodeni kubangela ukuqina.
4. Ukusebenza okujwayelekile kwendlala yesinye. Ngokuqukethwe okwengeziwe kwe-DHT esegazini, izicubu zesikhumba se-Prostate ziqala ukukhula. Kulokhu, sesivele sikhuluma nge-adenoma yesibindi. Ezimweni ezimbi kakhulu, kuvela isimila esibuhlungu.

Inani elijwayelekile le-dihydrotestosterone emadodeni aneminyaka engu-15 ngu-250-990 pg / ml. Ngokwanda noma ukuncipha kwalezi zinkomba, sesivele sikhuluma nge-pathology.

Kungani i-DHT iphakanyisiwe?

Amanani akhuphukayo e-dihydrotestosterone abonwa emadodeni asebenzisa ama-anabolic steroid ngenhloso yokwakha izicubu zomzimba. Kumele kukhunjulwe ukuthi kuyingozi enkulu ukusebenzisa izidakamizwa ze-hormonal ngokungadingekile.

Lokhu kungenxa yokuthi ngemuva kwenkambo enjalo, i-testosterone yamahhala iguqulwa ibe yi-estrogen, futhi ukuhlanganiswa kwe-testosterone kuyancishiswa. Izinga le-prolactin, estradiol ne-estrogen lenyuka ngemuva kokuthatha ama-anabolic steroid. Lokhu kugqame nentuthuko yokuhluleka kwe-hormonal.

Ukuze ugweme lokhu, kungcono ukusebenzisa inhlama yenhlama yemvelo ukwandisa izinkomba zamandla. Zizosiza ukukhulisa amandla kanye namazinga e-testosterone amahhala egazini ngaphandle kokulimaza impilo. Okwamukelekayo kusuka endaweni yokubuka yokuphepha yincwadi yokuhlola i-Yarsagumba Forte.

Uma i-dihydrotestosterone iphakanyisiwe, kungahle kube nezinye izizathu:

• Isifo sayo i-Itsenko-Cushing. Lesi sinqamuleli sisho ukugula lapho kwakhiwa khona i-pituitary microadenoma.
• Ukuvela kwamathumba amabi ku-adrenal gland. Kepha ukwanda kwe-DHT kungabonakala nasezimeni lapho isimila singalulanga.
• I-testosterone toxicosis. Ngaphansi kwalesi sifushaniso kuyindlela yokusebenza lapho i-hyperplasia yokuzalwa yamaseli eLeydig ibonwa khona.
• I-Benign prostatic hyperplasia. Lapho kuvela lokhu kugula, kuba khona ukuphazamiseka kwezifo ezibonakala emzimbeni. Kuzo zonke izimo, kukhona izinga elikhulayo le-dihydrotestosterone. Ngaphezu kwalokho, izinkomba zingakhuphuka ngokuhamba kwesikhathi futhi ezigabeni zokuqala zokuqhubekela phambili kwe-BPH.

Ukwanda kwe-dihydrotestosterone emadodeni kuyabonakala nangaphambi kokuba khona kweMorris syndrome. Ngaphezu kwalokho, ngalesi sifo, umuntu one-chromosome Y angaba nesitho sangasese sowesifazane esidaliwe.

Izimpawu Nokuxilongwa

Ezimweni lapho i-dihydrotestosterone iphakanyiselwe khona emadodeni, ukwenziwa kwabantu besifazane kuyabonakala. Isiguli sinokwehla okubonakalayo kwephesenti lamasipha omzimba, ukwehla kokukhula kwezinwele ebusweni nasemzimbeni, kanye nokwehla kwe-libido. Cishe ngaso sonke isikhathi kukhona i-flaccid penis noma i-erectile dysfunction.

Ezimweni ezisezingeni eliphakeme zomtholampilo, isithombe siphinyiselwa nangokwengeziwe. Kukhona ukuvuvukala kwezindlala ezincelisayo. Imvamisa, izingono zilimaza futhi zilume. Kwenzeka ukuthi ukwanda kwe-DHT kuthinte isikhumba. Isibonelo, induna nokuqhuma kungavela esikhunjeni.

Kunezimbangela eziningi zokwanda kwe-dihydrotestosterone emadodeni. Ngakho-ke, umgomo wokuxilongwa ukhethwe ngamunye ngokusekelwe eziphethweni zikadokotela oholayo. Kepha kuzo zonke izimo, lapho kunezimpawu zobuntu besifazane, kuhlaziywa ukwenziwa kwezinga le-DHT.

Ukuze ucwaningo luthembeke, isiguli kufanele:

1. Ungadli ukudla ngosuku ovivinya ngalo ama-hormone ocansi. Ungaphuza kuphela amanzi ngaphandle kwegesi.
2. Izinsuku ezingama-2-3 ngaphambi kokuhlaziywa, wenqaba ukuphuza utshwala nokubhema.
3. Izinsuku ezingama-1-2 ngaphambi kokuhlaziywa, yenqaba ukudla ukudla okunamafutha.
4. Yekani ukusebenzisa izidakamizwa ze-hormonal neminye imithi engaphambanisa imiphumela yokuhlaziywa.

Ngokusekelwe emiphumeleni yezivivinyo, udokotela unquma imbangela yokwanda kwe-DHT, futhi ukhetha ukwelashwa okufanele.

Yini okufanele uyenze ngamazinga aphezulu we-DHT?

Ukwelapha amacala emitholampilo lapho i-dihydrotestosterone emadodeni iphakanyisiwe, kuyadingeka ngendlela ephelele. Uma ama-neoplasms ku-adrenal gland eba imbangela yokwanda kwe-DHT, kunikezwa ukwelashwa okuhlinzwa. Uma kunesidingo, i-radiation therapy kanye ne-chemotherapy esetshenziswa ngemuva kwenqubo.

Uma umsebenzi owandisiwe we-5-alpha-reductase ubonwa, bese kukhuphuka i-dihydrotestosterone, kusetshenziswa ama-inhibitors ama-5-alpha-reductase. Imvamisa, izidakamizwa ezifana ne-Avodart, Finasteride, Dutasteride ziyasetshenziswa.

Ukwehlisa izinga le-DHT, izidakamizwa ezinomphumela we-antiandrogenic nazo zingasetshenziswa. Ziyi-2 izinhlobo:

• I-Steroidal. Ama-antiandrogens asebenza ngempumelelo avela kuleli qembu yi-Spironolactone, iCyproterone Acetate, Megestrol Acetate.
• Okungeyona i-steroidal. Phakathi kwama-anti-androgens angewona ama-steroidal, ahamba phambili yiCasodex, Anandron, Flutamide.

Uma i-DHT iphakanyisiwe kumfana, khona-ke kusetshenziswa ama-analog ama-hormone okwenziwa isikhathi eside kweLutropin.

Ukwelashwa kwamazinga aphezulu e-DHT ngenxa yesifo se-Itsenko-Cushing, i-testosterone toxicosis, kanye nokuvela kokuzalwa kwe-steroidogenesis kwenziwa ngokwelashwa.

Kepha hhayi ngaso sonke isikhathi ngosizo lwezidakamizwa kungenzeka ukufeza imiphumela ephezulu. Isibonelo, isifo sika-Itsenko-Cushing singalashwa nge-adrenalectomy noma i-proton therapy. Umphumela omuhle kakhulu ungatholakala ngokusebenzisa ukubhujiswa kwezindlala ze-adrenal ngokungenisa i-ejenti ephambene ebhubhisa isakhiwo sabo.

Njengoba wazi, i-DHT ephakeme imvamisa kakhulu ingumphumela we-prostatitis ne-adenoma. Ukwelashwa kwalezi zifo zesilisa kwenziwa ngokwelashwa. Kulokhu, ama-peptides we-bioregulatory, ama-antibiotic, ama-inhibitors ama-5-alpha-reductase, ama-alpha-1-adrenergic blocking agents, ama-analgesics, ama-antispasmodics asetshenziswa.

Ungawehlisa kanjani i-dihydrotestosterone

Ukwehlisa amazinga e-dihydrotestosterone kuyadingeka ukucindezela umsebenzi we-enzyme uyihlanganisa - i-5-alpha-reductase. Kulokhu, kusetshenziswa izinhlobo ezi-2 zezidakamizwa (ama-DHT blockers): kususelwa ku-finasteride ne-dutasteride.

I-Finasteride ("I-Penester" ne "Proscar" - amaphilisi aqukethe i-5 mg yesithako esisebenzayo, "Propecia" - 1 mg) is ahibitor ekhethiweyo ye-enzyme (emabhuloki ayi-5-alpha-reductase uhlobo 2), isebenza kakhulu ku-prostatic hyperplasia ne-alopecia. Lapho kusetshenziswa i-Finasteride, i-serum DHT yehla cishe ngama-70%. Imiphumela yokwelashwa yokwehlisa izinga le-dihydrotestosterone iyaboniswa emva kwezinyanga ezi-3 zokuphathwa kwezifundo -ukuncipha okumakwe umthamo we-prostate kulungisiwe, ukugcwala kwesikhumba kanye nobuso bujwayelekile.

Yehlisa izinga le-dihydrotestosterone egazini nezicubu zomgogodla we-Prostate. Inqanda umphumela ovuselelayo we-DHT ekuthuthukiseni i-adenoma yesibindi. Intengo emakhemisi cishe ama-ruble angama-500

Ngemiphumela emibi yokuthatha i-Finasteride, kukhona ukwehla kwesisindo sezinhlayiya zama-testicles, ukuwohloka ku-morphology kanye nokuhamba kwe-spermatozoa, ukubukeka kokudangala nokukhathazeka okungapheli. Uma isifundo sikhanseliwe, izimpawu ze-hyperplasia ziyabuya ngemuva kwezinyanga ezingama-6-8. Ngonyaka wokuqala wokwelashwa, amadoda angaba nokukhubazeka, ukwehla okuphawulekile kwe-libido ("postfinasteride syndrome"). Ngemuva kweminyaka engu-2 -4 yokwelashwa, lo mphumela wecala uvama ukudamba, kepha hhayi njalo.

I-Dutasteride (Avodart, Urofil, Alfinal) ishibhibhi esizukulwaneni sesi-2; ivimbela ngokushesha izinhlobo eziyi-1 nezingu-2 ze-alpha reductase isoenzymes. Amazinga we-Dihydrotestosterone ancishiswa abe ubuncane ngemuva kwamasonto angu-1-2 wokuphatha. Lento isebenza kahle kune-Finasteride − izinga le-serum dihydrotestosterone lehliswa ngo-95%. Izidakamizwa ezenzelwe i-Dutasteride zivame ukusetshenziselwa ukwakhiwa komzimba ukukala imiphumela emibi ye-androgenic yama-steroid athile (i-alopecia, okuqukethwe kwamafutha okuphezulu kwesikhumba nobuso, induna). Kepha ngasikhathi sinye, umthelela ongemuhle nawo uyabonakala ngesimo sokuncipha kwamandla onke kanye nokuqina kwemisipha, kanye nokuwohloka kwe-potency. Amanye amadoda aphoqeleka ukuthi athathe i-Viagra ngenxa yokungasebenzi kahle kwe-erectile. Kungenzeka futhi ukuthuthukiswa kwe-gynecomastia ngenxa yokucindezelwa kokuvikelwa kwe-antiestrogenic kwe-dihydrotestosterone. Imiphumela emibi ejwayelekile ekuthatheni zombili izinhlobo ze-blockers nayo iyavuvukala, ukulunywa, okhalweni, imivimbo.

Ngaphezu kwe-5-alpha reductase inhibitors ukunciphisa i-dihydrotestosterone kwezinye izimo, izinto ze-antiandrogenic ziyasetshenziswa: flutamide, spironolactone.

Njengokwelashwa kwendawo ekwelapheni ukusetshenziswa kwe-baldness "Minoxedil", etholakala ngesimo sokufafaza noma isixazululo. Ezimweni ezimbi kakhulu, ama-follicles wezinwele atshalwa kusuka ezingxenyeni ezizimele ze-androgen.

Ukwehlisa izinga le-dihydrotestosterone emadodeni asemasha, odokotela bazama ukungasebenzisi izidakamizwa ze-hormonal, ukuze bangaqedi ukushoda kwe-androgen. Amakhambi we-Folk kanye nezithasiselo zokudla kungasiza ukunciphisa izinga lamahomoni asebenzayo:

• Ishaye i-nettle
• Ukukhishwa kwezithelo zesundu esenziwe ngodonga: "Prostaplant", "Permikson", "Prostakur",
• I-Vitamin B ne-zinc nayo inomthelela ekunciphiseni komsebenzi we-5-alpha reductase. Ukucebisa umzimba ngalezi zinto ekudleni kufanele kufake izinhlanzi, isibindi senkomo, ummbila, amasoso, imbewu yethanga.

Ngokungasebenzi kahle noma ngokungafanele kwekhambi lokwelashwa, i-prostate gland noma i-adrenal neoplasms iyasuswa.

Ukwanda kwe-dihydrotestosterone

Khulisa amazinga e-dihydrotestosterone nge kwehlise i-testosterone ingavuswa ukukhiqizwa kwama-hormone noma ukuphathwa kwama-steroid angaphandle. Esimweni sokuqala, kusetshenziswa i-chorionic gonadotropin, i-thioctic acid, izidakamizwa ze-antiestrogen ezisuselwa ku-clomiphene citrate noma i-tamoxifen.

Uma ukwelashwa okuqhubekayo okunye esikhundleni kuyadingeka, i-testosterone yangaphandle inqunyelwe., ongaba ngesimo semijovo, amaphilisi, amagiya, okokugcotshwa kwama-hormonal noma izingqimba ze-transdermal. Umuthi wesizukulwane sokugcina nguNebido. Ukugcina izinga elijwayelekile le testosterone (ngokulandelana, ne-dihydrotestosterone), umjovo owodwa njalo ezinyangeni ezi-3-4 kwanele. Izinzuzo eziyinhloko: akunamphumela omubi esibindini, izinso kanye ne-Prostate gland, akukho ukwehla kwehomoni.

Ukusetshenziswa kwansuku zonke kwama-testosterone patches nama-gels (Androgel) nakho kunikeza ukwanda kwezinga lama-androgens, kepha lezi zinhlobo azilungeleki kakhulu ngenxa yesidingo sokulungiselela isikhumba, amathuba okucasulwa, kanye nokungafinyeleleki kokuxhumana nabantu bezinto zesikhumba zabanye abantu (lapho kusetshenziswa okokugcoba namagiya).

Uma testosterone evamilekhona-ke kusetshenziswa amalungiselelo e-dihydrotestosterone (ijeli le-Andraktim, amaphilisi).

Ungalijamisa kanjani izinga le-DHT

Indlela enkulu yokwelapha ukuphazanyiswa kwemfihlo kwe-DHT ukwelashwa ngezidakamizwa. Imithi ethile kanye nesikhathi sokwelashwa kunqunywa udokotela.

Ukwehla kwezinga le-dihydrotestosterone emikhubeni yemitholampilo yenziwa kusetshenziswa ama-androgenidal ama-androgenidal kanye ne-non-steroidal. Le mishanguzo ivimbela ukwakheka kwe-DHT noma ivikele ukubopha kwayo ukubhekisa kuma-cell receptors. Uma kwenzeka ukukhula kokuya ocansini ngaphambi kwesikhathi ezinganeni zesilisa, ama-ejenti asetshenziselwa ukuthi anciphise ukukhululeka kwama-hormone e-pituitary gland kanye ne-hypothalamus. Uma i-dihydrotestosterone iphakanyisiwe kwabesifazane, izidakamizwa eziqukethe i-metformin ne-spironolactone zinqunyelwe. Ngomsebenzi owandayo we-5-alpha reductase inhibitors yale enzyme asetshenziswa.

Uma ukuphambuka kwezinga lama-hormone kusuka kokujwayelekile kuhlotshaniswa nokuqubuka kwezindlala noma ama-testicles e-adrenal, ukwelashwa okuhlinzwa noma imisebe ye-neoplasm kuyadingeka.

Uma izinga le-hormone lehliselwa, kunqunywa ukwelashwa okufakwa esikhundleni se-hormone.

Endabeni yokuphazamiseka kokusebenza, kungenzeka ukwenze kube ngokwejwayelekile ukulinganisela kwe-hormonal ngaphandle kwemithi ngosizo lokulungiswa kwendlela yokuphila: ukudlala imidlalo, ukulungisa isisindo somzimba, ukwenza umsebenzi ube nokujwayelekile futhi uphumule, ukuyeka imikhuba emibi. Ukudla okulinganiselayo kungakhuphula izinga le-androgens ngezinga elithile - ukudla kufanele ukucebiswa ngamavithamini, amaminerali namaprotheni. Kubalulekile ukugwema ukucindezelwa kwengqondo nokomzwelo, njengoba i-cortisol ekhishwe ngesikhathi sokuxineka ivimbela ukwakheka kwamahomoni ocansi abesilisa.

Ividiyo evela ku-YouTube esihlokweni sendatshana:

Imvamisa kubantu besifazane

Nguye ohlinzeka ngokuthuthuka okuvumelanayo kwezitho nezinqubo, enika owesilisa izimpawu zamakhono obudoda, kanye nowesifazane onesifazane.

Izitho zokuzitholela kwangaphakathi zabamele bobabili ubulili zikhiqiza “isethi” yama-hormone, afaka phakathi ama-estrogens (owesifazana) kanye no-androgens (owesilisa).

Ukubekwa phambili komunye nomunye kunquma ubulili bomuntu.

Ukuba khona kwe-dihydrotestosterone kwabesifazane kubalulekile emthethweni:

• izidakamizwa ze-sebaceous zisebenza ukuqinisekisa ukujuluka okujwayelekile,
• ukuthuthukiswa nokukhula kwamathambo nemisipha,
• ukwakheka nokukhula okujwayelekile kwezinwele,
• izinhlobo ezahlukahlukene zokushintshana,
• libido.

Le hormone ebalulekile ivikelwa ama-ovari kanye ne-adrenal cortex. Inkomba ejwayelekile ye-dihydrotestosterone emzimbeni womuntu wesifazane isukela ku-5 kuye ku-450 pg / ml.

Kuya ngeminyaka:

• emzimbeni wamantombazane angaphansi kweminyaka eyi-10, iqukethe kuphela u-5 kuya ku-25 pg / ml,
• emantombazaneni amadala - B 24-450 pg / mg,
• esikhathini se-postmenopausal, izinga layo lehlela ku-10-181 pg / ml.

Ukwanda kwesilinganiso samahomoni wesilisa, lapho lokhu kungeyona i-pathology, kuyabonwa:

• ngesikhathi sokuthomba kwamantombazane, lapho ukwakhiwa kwezimpawu zobulili zesibili kwenzeka,
• emzimbeni wabesifazane abakhulelwe.

Ubudlelwano obuphakathi kwe-dihydrotestosterone nokulahlekelwa izinwele buye buqonde kakhulu. Yile hormone ehola amadoda ebunqwabeni.

Mayelana nezizathu zokunciphisa i-testosterone emadodeni ifundwe lapha.

Uyini umehluko phakathi kwe-testosterone yamahhala nephelele? Uma unesifiso, funda le ndatshana.

Izizathu zamazinga e-dihydrotestosterone akhuphukile

Isizathu sokuxhuma okungenakulungiswa ngokomzimba ngenani lamahomoni owesilisa emzimbeni wowesifazane kungaba:

• inqubo yesimila (ngokwesibonelo, i-polycystic ovary),
• ukuphazamiseka kokusebenza ohlelweni lwe-endocrine,
• Izinkinga ze-carbohydrate metabolism (ngokubekezelela ushukela),
• ukuphazamiseka kokusebenza kwesibindi okuhambisana nokukhiqizwa kwe-globulin, ukuntuleka kwayo okungavumeli izitho nezinhlelo ukuthola ama-hormone abesifazane ngenani elifanele,
• ukuthatha izidakamizwa ezinama-hormone.

I-ovary enempilo ne-polycystic

Imiphumela ingaba:

• ukwephula umjikelezo wokuya esikhathini kuze kube ukungabikho komthethonqubo ophelele, okwenza ukukhulelwa kungenzeki,
• ukwakheka kohlelo lwe-musculoskeletal ngokohlobo lowesilisa,
• ukubukeka komqubuko kanye nokuqubuka komqubuko esikhumbeni sobuso, esifubeni nasemhlane,
• ukuqina kwezwi
• ukwanda kolaka
• ukulahleka kwezinwele ekhanda nokukhula kwazo okukhulu ezindaweni ezingejwayelekile kwabesifazane: ebusweni, esifubeni nasemhlane,
• i-endometrial hyperplasia, lapho isimo sakhe singashintshi okuvamile kwezomfihlo,
• ukukhuluphala kohlobo lowesilisa, ngesisindo somzimba ophezulu. Njenganoma yikuphi ukuzuza ngokweqile kwesisindo, kungadala isifo sikashukela.

Uterine endometrial hyperplasia

Ukuvela kwezimpawu zesilisa "kwabesilisa" kufanele kuqwashise futhi kusetshenziswe njengesizathu sokuhambela kwe-endocrinologist ukuhlola izinga lakho le-dihydrotestosterone.

Zonke lezi zinkathazo ziyalungiswa uma isizinda se-hormonal silungiswa ngesikhathi nangendlela efanele.

Ngabe ngidinga ukulungiselela ukuhlolwa

Noma iyiphi indlela iqala ngesinyathelo sokuqala, nanoma yikuphi ukwelashwa okuxilonga. Ukuhlolwa kwegazi kwama-hormone isinyathelo sokuqala sokuthola izimbangela zokukhiqizwa ngokweqile kwe-dihydrotestosterone. Ukuhlaziywa akudingi ukulungiswa okhethekile ngakwesifazana, kodwa kubalulekile ukwazi ukuthi unikela ekuseni ngesisu esingenalutho.

Kunconywa ukwenza lolu cwaningo ngosuku lwe-6-7 lomjikelezo "wabesifazane".

Usuku ngaphambi kokuya egumbini lokucwaninga, kufanele:

• yekela ukubhema
• khipha ukudla okunamafutha nokuthosiwe ekudleni,
• gwema ukucindezela kanye nokuzivocavoca ngokweqile.

Udokotela oholayo kufanele aqaphele yonke imishanguzo ethathwa yilowo wesifazane ohlolwa. Ezinye zazo kungadingeka zikhanselwe kafushane.

Ukwanda kwe-dihydrotestosterone kwabesifazane - ukwelashwa

Izindlela zokubhekana ngokweqile kwe-dihydrotestosterone zixhomeke kuzizathu ezenze ukuthi ifinyelele, futhi zikhethwe ngawodwana.

Uma ukungalingani kwe-hormonal kususelwa ekuphazamisekeni kokusebenza kwezitho zomzimba (ngokwesibonelo, isibindi), khona-ke ukwelashwa kuqala ngokubuyiselwa kwemisebenzi yabo.

Kwezinye izimo, kusetshenziselwa ukwelashwa kwe-hormonal therapy: ama-estrogenythi anqunyelwe ukwenza isenzo se-androgener, sinciphise owesifazane wezimpawu "zesilisa". Ukwenza ngokwejwayelekile izinga lamahomoni owesilisa emzimbeni wowesifazane, izidakamizwa ezifana:

• I-Diethylstilbestrol iyi-estrogen eyakhiwe.
• I-Diane 35 ilungiselelo elihlanganisiwe lesenzo se-estrogenic ne-antiandrogenic.
• I-Dexamethasone iyi-synthetic glucocorticoid evamile ukuthi iprotheni, i-carbohydrate kanye ne-mineral metabolism.
• ICyproterone yi-androgen receptor blocker esehlisa imiphumela yama-hormone wesilisa emzimbeni.

Kwenzeka ukuthi ukwelashwa kwe-hormone kuphambaniswe nentombazane. Kube sekuqokwa uVeroshpiron. Isebenza ngendlela yokuthi ukuzwela komzimba ku-dihydrotestosterone kumane kuvinjelwe. Inani le-hormone, alas, alinciphi, kepha ukuba khona kwalo egazini akulithinti noma yini.

Uma imbangela yezinga elandayo lama-androjeni ingenxa yezinqubo zesimila, khona-ke isinqumo siyenziwa ekususweni kokuhlinzwa kwezimila. Ngakho-ke, inkinga ye-dihydrostestosterone eyeqile iyasuswa.

Abesifazane abanokukhuluphala kwama-degree ahlukahlukene futhi bahlushwa i-dihydrotestosterone ngokweqile kudingeka baqale ukwelashwa ngezindlela okuhloswe ngazo kurejista isisindo somzimba: shintsha indlela abadla ngayo futhi bafake iqoqo lokuzivocavoca umzimba okhethekile ezinhlelweni zabo zansuku zonke.

Kungenzeka ukuthonya ukwehla kwezinga le-dihydrotestosterone ngokudla okukhethekile nokuqukethwe okuphezulu kwemikhiqizo ecebile nge-estrogen:

• ama-apula nama-cherries amamaki ahlukahlukene,
• amazambane, izaqathe neminye imifino,
• inyama nemikhiqizo yesoya,
• okusanhlamvu (ukolweni nelayisi),
• skim ubisi no-ayisikhilimu
• ushukela.

Ngaphezu kwezindlela zokwelapha zesimanje, kunezindlela zemithi yendabuko. Ama-herbalists athi ukuthatha ama-tincture kanye nama-decoctions kusuka ezitshalweni angathinta kahle isizinda se-hormonal, kubuyisele kokujwayelekile.

Ephawula ngalesi sitatimende, ochwepheshe bezokwelapha bengeza ukuthi ukusetshenziswa kwezinye izindlela zokwelashwa kuleli cala kunganikeza umphumela omuhle kuphela ngokungalingani okuncane kwe-hormonal.

I-Dihydrostestosterone emzimbeni wesifazane ibhekene nokukhula kwe-libido nokukhula kwezinwele.Mayelana nokuthi yini okufanele ibe yinto evamile ye-dihydrotestosterone egazini lowesifazane, funda kulesi sihloko.

Izindlela eziphambili zokwandisa testosterone kwabesifazane zichazwe kulesi sihloko.

Kungcono ukuhlanganisa ukwelashwa ngamakhambi nezindlela zokwelapha ezibekwe udokotela wakho - Kuzoba nokuzuzisa okwengeziwe. Into esemqoka ukungazithibisi, ukhetha "amalungiselelo abantu" bese usetha umthamo wabo ngokubona kwakho.

Ngendlela, enye yezindlela ezilula nezisebenzayo zokuvimbela ukukhiqizwa kwe-dihydrotestosterone kubhekwa njengokujwayelekile kuwo wonke umuntu itiye kusuka ephepermermint ejwayelekile.

Umzimba wowesifazane nokujwayelekile kwehomoni dihydrotestosterone

Ngokusebenza okujwayelekile komzimba, ukulinganisela kwama-hormone kubalulekile. Ukuba khona kwe-estrogen kunomthelela ekuthuthukisweni kohlelo lokuzala, ukuzinza komjikelezo wokuya esikhathini. I-Dihydrotestosterone kwabesifazane yenza imisebenzi eminingana:

Le hormone ikhiqizwa izindlala nama-adrenal maqanda. Kudingeka umzimba ngenani elincane. Izinga le-dihydrotestosterone kwabesifazane lincike eminyakeni yobudala futhi lisuka ku-24 liye ku-450 pg / l.

Ukwanda kwe-DHT kuthinta umzimba ngokushesha.

Izimpawu zamazinga akhuphukile we-DHT: ukulahleka kwezinwele nabanye

Okokuqala, lezo zitho ezithinta ngqo i-DHT ziyathinteka. Isibonelo, i-dihydrotestosterone nokuncipha kwezinwele kwabesifazane kuhlobene ngqo. Le yinkinga evame ukubhekana nazo ngamazinga akhulayo aleli mahomoni. Uma i-hormone inqwabelana kumabhuleki, umsebenzi wawo uyawohloka, okwenza izinwele zibe brittle ne-oily. Kamuva, lokhu kuholela ekulahlekelweni kwabo.

Ukweqiwa kwe-DHT kuthinta nesikhumba ngokwanda kokuqukethwe kwamafutha ngenxa yokuphazamiseka kwe-metabolic. Lokhu kubangela ukukhuluphala, ikakhulukazi emzimbeni ophezulu.

Enye inkinga eziveza ngokwanda kwezinga le-dihydrotestosterone emadodeni nakwabesifazane ukukhula kwesifo sikashukela. Lokhu kungenxa yokuthi i-glucose excretion iyinkimbinkimbi kumaseli.

Kumantombazane asakhula, ukwanda kwe-DHT egazini kudala ushintsho ekukhuleni kwamathambo kufomu lowesilisa. Ngaphezu kwalokho, amantombazane abe nokuhlangana kwezwi, ukwephula umjikelezo noma ukungabikho kokuya esikhathini ngokuphelele. Kwabesifazane abadala, lokhu kungadala ukungasebenzi kahle kohlelo lokuzala, kuze kube sekukhuleni kokuzala.

Ukwanda kwamazinga ama-hormone kwenzeka:

Isizathu sokwanda kwe-dihydrotestosterone emadodeni nakwabesifazane kungaba ukwephula isibindi. Lo mzimba ukhiqiza i-globulin, omolekyuli bayo abaxhumana nama-hormone ocansi.

Uma amazinga aphezulu e-DHT eqhubeka isikhathi eside, lokhu kungaholela ezinkingeni ezinkulu. Kulesi simo, isimo somzimba silinganiswa ngochwepheshe njengokunamandla.

Yiziphi izivivinyo okufanele uzithathe nokuthi ungazilungiselela kanjani

Uma udokotela esola ukwanda kwezinga le-DHT egazini, uqoka ukuhlaziya okhethekile.

Lokhu kuzonquma izinga le-hormone nezizathu zokunyuka kwayo. Nikeza ukuhlaziya lapho isiguli sine:

Ngaphezu kwalokho, intsha inikezela lokhu kuhlaziya ukuthola inani lama-hormone nomphumela wazo ekuthuthukisweni kohlelo lokuzala.

Akudingi ukuqeqeshwa okukhethekile. Ukuqoqwa kwenzeka ekuseni ngesisu esingenalutho. Odokotela balulekisa ukukukhipha ngaphandle ukusetshenziswa kwamafutha nokudla okuthosiwe, ukubhema, ukuvivinya umzimba kakhulu ngaphambi kokuthatha isivivinyo.

Yazisa udokotela ngokuthatha umuthi. Kwezinye izimo, kunconywa ukuthi kumiswe ukusetshenziswa kwabo ezinsukwini ezimbalwa ngaphambi kokuqoqwa kokuhlolwa.

Ukwelashwa kwamazinga aphezulu we-DHT: inqubo yokwehlisa ukusebenza kwezidakamizwa nemithi yabantu

Ukwelashwa kukhethiwe ngakunye, kuye ngezimbangela zesifo. Uma i-dihydrotestosterone iphakanyisiwe kowesifazane ohlela ukukhulelwa, khona-ke unikezwa imithi yokuvuselela i-ovulation.

Ngaphandle kwalokho, izidakamizwa ze-hormonal zisetshenziselwa ukuvimbela ukukhulelwa.Banomphumela ocindezelayo kuma-androgens.

Ezimweni lapho imbangela yalesi sifo kungukuncipha koshukela amaseli, kuhlangene nesisindo esandisiwe, ukudla okunama-carb aphansi kunikezwa njengokwelashwa. Kuzokuvumela ukuthi ukhiphe amakhilogremu angeziwe futhi wenze nokulinganisela kwe-hormonal usawa

Ngezifo eziyinkimbinkimbi ezibangela ukwanda kwezinga le-dihydrotestosterone kwabesifazane: ukwelashwa nge-metformin, naku-gynecology nge-spironolactone. Ukusebenza kwabo kungenxa yokuvinjwa kokuguqulwa kwe-testosterone kuyi-DHT.

Ukuze uthole ukwelashwa okuphelele futhi okusebenzayo, kuyadingeka ukuthi uhlolwe bese uthola izincomo zochwepheshe be-endocrinologist.

I-Dihydrotestosterone ekungalingani kwamadoda nokuthi wenzeni ngokwanda

I-Dihydrotestosterone yi-hormone ebaluleke kakhulu emzimbeni wesilisa. Kungumkhiqizo wokuhlanganiswa kwe-testosterone nama-enzyme axhumana nayo.

Unesibopho sokukhula, ukukhula kwezitho zangasese kanye nokuqina kwendlala, ukuvuthwa okufanele ebusheni.

Ukukhiqizwa kwe-DHT kwenzeka ezivivinyweni, kuthi ukuqoqwa okuphezulu kakhulu kwento kugxiliswe kunombolo yama-epithelial ye-genitals kanye ne-follicles yezinwele.

I-Dihydrotestosterone ikhona emzimbeni wabesifazane nowesilisa, noma kusukela esibelethweni. Kuyo yonke impilo, emadodeni inani lawo lenyuka ngamagagasi.

Esontweni lokuqala ngemuva kokuzalwa, izinga le-hormone kubafana lisuka ku-2,5 liye ku-10 μm / L, bese liyancipha futhi kuze kube seminyakeni emithathu okuqukethwe kwalo kucishe kube ngu-0.6 μm / L.

Ngeminyaka engu-6, inani likhuphukela ku-5 μm / l, futhi ngo-8 lehla ngesigamu. Ebusheni, ukuqina kwayo egazini kukhuphuka kancane kancane kusuka ku-2,5 kuye ku-10 microns / ilitha.

Inani eliphakeme kakhulu le-dihydrotestosterone lifinyelelwa eminyakeni engama-25, ngemuva kwalokho kwehle cishe ngo-2 - 3% ngonyaka.

Ngenkathi ingane isesesibelethweni, into ethinta ukukhula kwama-testes kanye ne-genitalia yangaphandle. Ekuthweni, izinga le-DHT lenyuka, izivivinyo ziyavuseleleka, izitho zangasese ziyakhula ngentshiseko, kusungulwa izici zokuya ocansini kwesibili, futhi ukukhiqizwa kwesidoda kuqale.

I-Dihydrotestosterone emzimbeni wesilisa ivuselela uhlelo lwezinzwa, ukusebenza kwezinduna ze-sebaceous nezikhwanyana zezinwele, kunesibopho sokukhula kwezinwele. I-hormone ibalulekile ekusebenzeni okujwayelekile kohlelo lokuzala, ibhekene nesifiso sobulili, imizwa evusa amadlingozi nemizwa yezocansi.

Imvelo yale nto ye-steroid esegazini iyahlukahluka ngokuya ngeminyaka, futhi incishiswa kakhulu emadodeni amadala. Uma izinga le-DHT liphambuka kulokho okujwayelekile esemncane, lokhu kuholela emiphumeleni ehlukahlukene, kufaka phakathi i-adenoma yesibindi.

Ngabe kuvela kanjani ukuphambuka

Ukuqanjwa kwe-hormone DHT emzimbeni wesilisa kuyancipha bese kuvela izimpawu ezibonisa ukungalingani kanye nokuntuleka kwayo. Ukulawula, ochwepheshe basungula izinkambiso eminyakeni ngayinye, ngokuya ngezinto ezahlukahlukene. Ukwehla noma ukwanda, okuholela ekuphambukeni emzimbeni.

Inani eliphansi laleli hormone liholela ku:

• ukubambezeleka kokuthomba ebusheni,
• ukuntuleka kwezimpawu zobulili zesibili,
• ukuqinisa imilenze
• okhalweni
• ukwehla kwesisindo semisipha
• kwehliswe i-sex drive,
• ukungabi namandla
• ukungazali
• ukukhuluphala
• isifo sikashukela
• i-prostate adenoma
• ukuntuleka kwe-libido
• ukuphambuka kohlelo lwezitho zofuzo.

Uma okuqukethwe kwe-DHT emzimbeni kudluliwe, khona-ke ungazibona lezo zimpawu:

• ukuthomba ngaphambi kwesikhathi,
• ukuncipha kwezinwele kuze kube yimpandla,
• hyperplasia ye-prostatic,
• i-hirsutism
• umdlavuza wendlala yesinye.

Ukuxilongwa okunembile, udinga ukubona udokotela, uzokwenza ucwaningo olunquma izinga le-DHT emzimbeni.

I-Dihydrotestosterone iphakanyisiwe emadodeni asebenzisa ama-anabolics e-steroid ukwandisa isisindo semisipha. Ngemuva kokulashwa okunjalo kwe-hormonal, i-testosterone yamahhala iguqulwa ibe yi-estrogen, futhi ukwakheka kwayo kuncishisiwe.Ngemuva kwenkambo yezidakamizwa ze-anabolic, izinga lamahomoni abesifazane emzimbeni wesilisa liyakhuphuka, lesi simo kungaholela ekwehlulekeni kwe-hormonal.

Okuqukethwe kwe-DHT egazini kukhuphuka ngalezi zizathu ezilandelayo:

• Isifo sayo i-Itsenko-Cushing,
• isimila esibuhlungu sezindlala noma amasende ama-adrenal,
• I-Leydig cell hyperplasia,
• indlala yesibindi eyandisiwe
• Isifo seMorris
• i-hypergonadism.

I-DHT ephansi ingenzeka uma owesilisa enenkinga yokuzalwa okungekuyo yesoftware. Uma umzimba ungenayo i-enzyme 5-alpha-reductase, khona-ke ukuvela kwe-testosterone akwenzeki.

Ezinganeni ezinalezi zifo, ama-pathologies endabuko ayaqashwa.

Ngokuncipha kwe-DHT yesiguli, impilo yezocansi iba nokunganaki, azizwe efisa ukusondelana, isifiso sobulili siyanyamalala.

Impilo yezocansi ihlobene ngqo nokusebenza kwezitho zangasese, ngakho-ke ukwehla kwekhwalithi yayo kungaholela ekuqothulweni kobudoda.

Ukwehla kwe-hormone dehydrotestosterone enobudala kugcwele ukuphambuka ekusebenzeni kwesistimu ye-nerve, genitourinary ne-inhliziyo.

Amakhambi esintu

Futhi, izindlela zokupheka ezinjengalezi zizosiza ukwehlisa izinga lamahomoni wesilisa:

1. Isanqante esisanda kufakwa - ujusi we-celery, okudingeka uwaphuze nsuku zonke, 1 ingilazi esiswini esingenalutho. Noma ungashintshana ngokuthatha isanqante kanye isilimo esidliwayo esinamagatsha anamanzi, inkambo ingamaviki ama-2.
2. Tea elinelayisense.

Kuyadingeka ukunquma impande ye-licorice kahle, engeza emaqabungeni etiyeni futhi uphuze i-mug yetiyi ngaphambi kokulala izinsuku eziyi-14. I-tincture yembewu yefilakisi. Thatha u-1 tbsp. l imbewu, uthele isigamu sengilazi yamanzi abilayo, amahora ambalwa, sebenzisa 1 tbsp. l ngosuku ngesisu esingenalutho.

Ngaphambi kokusebenzisa ukwelashwa kwendabuko, udinga ukubonana nochwepheshe.

I-Dihydrotestosterone emzimbeni idlala indima ebaluleke kakhulu, ibamba iqhaza ezinqubweni eziningi, futhi ukuphambuka kwayo esimweni kungaholela kuma-pathologies nezifo ezahlukahlukene.

Ngalesi sizathu, kubaluleke kakhulu ukubheka impilo yakho futhi unake amasiginali we-alamu akhombisa ukuba khona kokuphambuka.

Njengoba uke wabona izimpawu zokuphazamiseka kwe-hormonal, udinga usizo losizo lwezokwelashwa olufanele.

Ikhula kanjani i-dihydrotestosterone kubantu besifazane nokuthi iguqula kanjani izinkomba zefomu le-testosterone

Ama-hormone wesilisa amaningi emzimbeni womuntu wesifazane asithinta kabi isisindo, umjikelezo wokuya esikhathini, ikhono lokukhulelwa, izakhi zokubonakala, umzimba we-carbohydrate metabolism.

Ngokusebenza okungafanele kwama-ovari kanye nezindlala ze-adrenal, ukuhlushwa kwe-testosterone hhayi kuphela, kodwa nokwanda kwe-androgen kwesibili. I-Dihydrotestosterone (DHT) ikhiqizwa kuma-ovari kanye ne-adrenal cortex.

Ukuphambuka ezingeni lamahomoni wesilisa kukhombisa ngokushesha isimo somzimba.

Yini okufanele uyenze uma i-dihydrotestosterone iphakanyisiwe kwabesifazane? Izimbangela nezimpawu ze-hyperandrogenism, imiphumela engenzeka, izindlela zokwelashwa nokuvimbela i-pathology zichazwe esihlokweni.

Indima yama-hormone owesilisa emzimbeni wowesifazane

Uhlobo lwe-testosterone lwe-testosterone lubandakanyeka kulawulo lwezinqubo eziningi:

• igcina indawo eyanele yamathambo, isekela ukuvuselelwa kwezicubu,
• kuvimbela ukugcwala kwemisipha,
• kuthinta amandla we-libido,
• inikeza isendlalelo esifanele samafutha angaphansi,
• ilawula ukusebenza kwezindlala ze-sebaceous.

I-Dihydrotestosterone (DHT) isebenza kakhulu kunamanye ama-androgens. Ukushoda komlawuli obalulekile kuholela ezinguquko ezingathandeki emzimbeni wesifazane.

Ukweqisa kwe-androgen esebenza futhi kuthinta kabi uhlelo lokuzala, ukubukeka, kanye nokusebenza komzimba.

Ngokungafani ne-testosterone, i-DHT ayenzi izinguquko, ayiguquki kuma-estrogens futhi ivimba ukuguqulwa okufanayo kwe-testosterone ukukhulisa ukugcwala kwama-hormone ocansi abesifazane.

Izizathu zokuphambuka

Noma yikuphi ukuphambuka kuzinga le-DHT emzimbeni wesilisa kukhombisa ukuqhubeka kwe-pathologies.Empeleni, empilweni yeziguli zombili izinkomba eziphakeme kakhulu futhi imiphumela ephansi iyingozi.

I-Dihydrotestosterone ekungalingani kwamadoda nokuthi wenzeni ngokwanda

I-Dihydrotestosterone yi-hormone ebaluleke kakhulu emzimbeni wesilisa. Kungumkhiqizo wokuhlanganiswa kwe-testosterone nama-enzyme axhumana nayo.

Unesibopho sokukhula, ukukhula kwezitho zangasese kanye nokuqina kwendlala, ukuvuthwa okufanele ebusheni.

Ukukhiqizwa kwe-DHT kwenzeka ezivivinyweni, kuthi ukuqoqwa okuphezulu kakhulu kwento kugxiliswe kunombolo yama-epithelial ye-genitals kanye ne-follicles yezinwele.

I-Dihydrotestosterone ikhona emzimbeni wabesifazane nowesilisa, noma kusukela esibelethweni. Kuyo yonke impilo, emadodeni inani lawo lenyuka ngamagagasi.

Esontweni lokuqala ngemuva kokuzalwa, izinga le-hormone kubafana lisuka ku-2,5 liye ku-10 μm / L, bese liyancipha futhi kuze kube seminyakeni emithathu okuqukethwe kwalo kucishe kube ngu-0.6 μm / L.

Ngeminyaka engu-6, inani likhuphukela ku-5 μm / l, futhi ngo-8 lehla ngesigamu. Ebusheni, ukuqina kwayo egazini kukhuphuka kancane kancane kusuka ku-2,5 kuye ku-10 microns / ilitha.

Inani eliphakeme kakhulu le-dihydrotestosterone lifinyelelwa eminyakeni engama-25, ngemuva kwalokho kwehle cishe ngo-2 - 3% ngonyaka.

Ngenkathi ingane isesesibelethweni, into ethinta ukukhula kwama-testes kanye ne-genitalia yangaphandle. Ekuthweni, izinga le-DHT lenyuka, izivivinyo ziyavuseleleka, izitho zangasese ziyakhula ngentshiseko, kusungulwa izici zokuya ocansini kwesibili, futhi ukukhiqizwa kwesidoda kuqale.

I-Dihydrotestosterone emzimbeni wesilisa ivuselela uhlelo lwezinzwa, ukusebenza kwezinduna ze-sebaceous nezikhwanyana zezinwele, kunesibopho sokukhula kwezinwele. I-hormone ibalulekile ekusebenzeni okujwayelekile kohlelo lokuzala, ibhekene nesifiso sobulili, imizwa evusa amadlingozi nemizwa yezocansi.

Imvelo yale nto ye-steroid esegazini iyahlukahluka ngokuya ngeminyaka, futhi incishiswa kakhulu emadodeni amadala. Uma izinga le-DHT liphambuka kulokho okujwayelekile esemncane, lokhu kuholela emiphumeleni ehlukahlukene, kufaka phakathi i-adenoma yesibindi.

Ngabe kuvela kanjani ukuphambuka

Ukuqanjwa kwe-hormone DHT emzimbeni wesilisa kuyancipha bese kuvela izimpawu ezibonisa ukungalingani kanye nokuntuleka kwayo. Ukulawula, ochwepheshe basungula izinkambiso eminyakeni ngayinye, ngokuya ngezinto ezahlukahlukene. Ukwehla noma ukwanda, okuholela ekuphambukeni emzimbeni.

Inani eliphansi laleli hormone liholela ku:

• ukubambezeleka kokuthomba ebusheni,
• ukuntuleka kwezimpawu zobulili zesibili,
• ukuqinisa imilenze
• okhalweni
• ukwehla kwesisindo semisipha
• kwehliswe i-sex drive,
• ukungabi namandla
• ukungazali
• ukukhuluphala
• isifo sikashukela
• i-prostate adenoma
• ukuntuleka kwe-libido
• ukuphambuka kohlelo lwezitho zofuzo.

Uma okuqukethwe kwe-DHT emzimbeni kudluliwe, khona-ke ungazibona lezo zimpawu:

• ukuthomba ngaphambi kwesikhathi,
• ukuncipha kwezinwele kuze kube yimpandla,
• hyperplasia ye-prostatic,
• i-hirsutism
• umdlavuza wendlala yesinye.

Ukuxilongwa okunembile, udinga ukubona udokotela, uzokwenza ucwaningo olunquma izinga le-DHT emzimbeni.

I-Dihydrotestosterone iphakanyisiwe emadodeni asebenzisa ama-anabolics e-steroid ukwandisa isisindo semisipha. Ngemuva kokulashwa okunjalo kwe-hormonal, i-testosterone yamahhala iguqulwa ibe yi-estrogen, futhi ukwakheka kwayo kuncishisiwe. Ngemuva kwenkambo yezidakamizwa ze-anabolic, izinga lamahomoni abesifazane emzimbeni wesilisa liyakhuphuka, lesi simo kungaholela ekwehlulekeni kwe-hormonal.

Okuqukethwe kwe-DHT egazini kukhuphuka ngalezi zizathu ezilandelayo:

• Isifo sayo i-Itsenko-Cushing,
• isimila esibuhlungu sezindlala noma amasende ama-adrenal,
• I-Leydig cell hyperplasia,
• indlala yesibindi eyandisiwe
• Isifo seMorris
• i-hypergonadism.

I-DHT ephansi ingenzeka uma owesilisa enenkinga yokuzalwa okungekuyo yesoftware.Uma umzimba ungenayo i-enzyme 5-alpha-reductase, khona-ke ukuvela kwe-testosterone akwenzeki.

Ezinganeni ezinalezi zifo, ama-pathologies endabuko ayaqashwa.

Ngokuncipha kwe-DHT yesiguli, impilo yezocansi iba nokunganaki, azizwe efisa ukusondelana, isifiso sobulili siyanyamalala.

Impilo yezocansi ihlobene ngqo nokusebenza kwezitho zangasese, ngakho-ke ukwehla kwekhwalithi yayo kungaholela ekuqothulweni kobudoda.

Ukwehla kwe-hormone dehydrotestosterone enobudala kugcwele ukuphambuka ekusebenzeni kwesistimu ye-nerve, genitourinary ne-inhliziyo.

Ukuxilonga

Uma umuntu enyuse i-dihydrotestosterone, lokhu kukhombisa izifo ezithile. Ukuze unqume izinga le-hormone, kuhlolwa igazi.
Uma indoda ine-benign prostatic hyperplasia, khona-ke isifundo siyenziwa ukuqapha isimo futhi silandele izinguquko lapho kuthathwa imithi nge-enzyme 5-alpha reductase.

Ukuhlaziywa kumele kuthathwe ekuseni kusuka emahoreni angama-8 kuye kwayi-11, esiswini esingenalutho. Ngaphambi kokubeletha, ungaphuza amanzi ahlanzekile asasebenza, ungaphuzi i-tee, ama-juices, i-soda. Kusihlwa awukwazi ukudla ukudla okunamafutha, okubhemayo, okubabayo.

1 - 2 izinsuku ngaphambi kokuthatha isivivinyo, kuyadingeka ukukhipha ukuphuza utshwala nokubhema, ukuzikhandla ngamandla, kufaka phakathi ukuphakamisa isisindo nemidlalo esebenzayo. Kuyadingeka ukuyeka ukuphuza umuthi, kepha kuphela ngemuva kokubonana nodokotela.

Ngobusuku bokuhlaziywa, kufanele kugwenywe izimo ezicindezelayo, ngoba ihora phambi kwakhe udinga ukwehlisa umoya uphumule.

Kuphikisiwe ukwenza isifundo ngemuva kwe-ultrasound ne-X-ray, kanye ne-massage kanye ne-physiotherapy. Ihanjiswa ngemuva kwesikhathi esithile kaningana. Ukulandelela ukuguquguquka kwezimo nesikhathi sokulethwa kokuhlaziywa kumele kufane ncamashi.
Ukuthatha umuthi othile kungahlanekezela imiphumela yokuhlolwa, ngakho-ke ukubamba kwabo kumele kuxoxwe nodokotela wakho.

Ngokuqokwa kukadokotela

Umuthi wesimanjemanje awukafundi ukuthi ungayiqeda kanjani imbangela yokuphazamiseka kwama-hormone emzimbeni, kepha kubalulekile ukwenza izinga le-DHT libe ligazi ngesikhathi esifanele.

Uma uzithola ukhulisa noma wehlise ukuqina kwe-hormone, kunconywa ukuxhumana nodokotela oyi-urologist kanye ne-endocrinologist.

Izindlela zokwehlisa i-hormone emzimbeni zihlobene ngqo nembangela yokwanda, izici zesithombe somtholampilo kanye nesimo esivamile sesiguli.

Ama-ejenti wezokwelapha kanye nama-regimen okwelashwa anqunywa ngokuhlukile, lokhu kunqunywa iqiniso lokuthi izinqubo ze-hormonal emzimbeni ziyaxhuma.

Uchwepheshe kuphela owazi yonke imininingwane yohlelo lwe-endocrine, futhi angakwazi nokukhetha ukwelashwa. Ezimweni eziningi, izidakamizwa zibekiwe kucatshangelwa ukukhiqizwa kwakho kwama-hormone.

Ukwelashwa kwamadoda kukhethiwe kubanzi kusetshenziswa izindlela ezahlukahlukene namathuluzi.

Isibonelo, iziguli ezinamazinga e-dihydrotestosterone aphakeme kunokwejwayelekile anqunywa izidakamizwa ze-inhibitory ze-5-alpha reductase ukunciphisa i-testosterone synthesis.

Lokhu kufaka phakathi iSuprefact, Deslorelin, iBuserelin, iMedroxyprogesterone, iVeraplex, iSpironolactone.

Kepha kubalulekile ukwazi ukuthi kuphela uchwepheshe onolwazi ongabeka imishanguzo nesikhathi sokuphathwa, ukuzelapha uqobo kuholela ekungalingani kwama-hormone, kusenze sibe nzima lesi simo futhi sibe yingozi empilweni.

Amakhambi esintu

Futhi, izindlela zokupheka ezinjengalezi zizosiza ukwehlisa izinga lamahomoni wesilisa:

1. Isanqante esisanda kufakwa - ujusi we-celery, okudingeka uwaphuze nsuku zonke, 1 ingilazi esiswini esingenalutho. Noma ungashintshana ngokuthatha isanqante kanye isilimo esidliwayo esinamagatsha anamanzi, inkambo ingamaviki ama-2.
2. Tea elinelayisense.

Kuyadingeka ukunquma impande ye-licorice kahle, engeza emaqabungeni etiyeni futhi uphuze i-mug yetiyi ngaphambi kokulala izinsuku eziyi-14. I-tincture yembewu yefilakisi. Thatha u-1 tbsp. l imbewu, uthele isigamu sengilazi yamanzi abilayo, amahora ambalwa, sebenzisa 1 tbsp. l ngosuku ngesisu esingenalutho.

Ngaphambi kokusebenzisa ukwelashwa kwendabuko, udinga ukubonana nochwepheshe.

I-Dihydrotestosterone emzimbeni idlala indima ebaluleke kakhulu, ibamba iqhaza ezinqubweni eziningi, futhi ukuphambuka kwayo esimweni kungaholela kuma-pathologies nezifo ezahlukahlukene.

Ngalesi sizathu, kubaluleke kakhulu ukubheka impilo yakho futhi unake amasiginali we-alamu akhombisa ukuba khona kokuphambuka.

Njengoba uke wabona izimpawu zokuphazamiseka kwe-hormonal, udinga usizo losizo lwezokwelashwa olufanele.

Ikhula kanjani i-dihydrotestosterone kubantu besifazane nokuthi iguqula kanjani izinkomba zefomu le-testosterone

Ama-hormone wesilisa amaningi emzimbeni womuntu wesifazane asithinta kabi isisindo, umjikelezo wokuya esikhathini, ikhono lokukhulelwa, izakhi zokubonakala, umzimba we-carbohydrate metabolism.

Ngokusebenza okungafanele kwama-ovari kanye nezindlala ze-adrenal, ukuhlushwa kwe-testosterone hhayi kuphela, kodwa nokwanda kwe-androgen kwesibili. I-Dihydrotestosterone (DHT) ikhiqizwa kuma-ovari kanye ne-adrenal cortex.

Ukuphambuka ezingeni lamahomoni wesilisa kukhombisa ngokushesha isimo somzimba.

Yini okufanele uyenze uma i-dihydrotestosterone iphakanyisiwe kwabesifazane? Izimbangela nezimpawu ze-hyperandrogenism, imiphumela engenzeka, izindlela zokwelashwa nokuvimbela i-pathology zichazwe esihlokweni.

Indima yama-hormone owesilisa emzimbeni wowesifazane

Uhlobo lwe-testosterone lwe-testosterone lubandakanyeka kulawulo lwezinqubo eziningi:

• igcina indawo eyanele yamathambo, isekela ukuvuselelwa kwezicubu,
• kuvimbela ukugcwala kwemisipha,
• kuthinta amandla we-libido,
• inikeza isendlalelo esifanele samafutha angaphansi,
• ilawula ukusebenza kwezindlala ze-sebaceous.

I-Dihydrotestosterone (DHT) isebenza kakhulu kunamanye ama-androgens. Ukushoda komlawuli obalulekile kuholela ezinguquko ezingathandeki emzimbeni wesifazane.

Ukweqisa kwe-androgen esebenza futhi kuthinta kabi uhlelo lokuzala, ukubukeka, kanye nokusebenza komzimba.

Ngokungafani ne-testosterone, i-DHT ayenzi izinguquko, ayiguquki kuma-estrogens futhi ivimba ukuguqulwa okufanayo kwe-testosterone ukukhulisa ukugcwala kwama-hormone ocansi abesifazane.

Izizathu zokuphambuka

Ukhushulwa okwandisiwe kwe-dihydrotestosterone kungumphumela wesenzo sezinqubo ze-pathological emzimbeni wowesifazane. Uma kutholakala inani elandayo le-androgen emantombazaneni asakhula ngenkathi kumiswa umjikelezo wokuya esikhathini, khona-ke lokhu okwenzekayo kuvumelekile ngenkathi ukuhlelwa kabusha kwe-hormonal kuqhubeka. Kancane kancane, izinga lamahomoni wesilisa kufanele lisondele.

Uma umjikelezo ungajwayelekile, eminyakeni engu-1-2 ngemuva kokuqala kokuya esikhathini, udinga ukuxhumana nodokotela wezifo zamazinyo ukuze ucacisa izinga le-androgens. Ngokuphikisana nesizinda sokulungiswa okungafanele kwesizinda se-hormonal, ngamazinga aphezulu e-DHT, kungenzeka ukuthuthukisa ama-polycystic ovari, inzalo, i-hirsutism, izinkinga ngesimo sezinwele nesikhumba.

Funda ngezimpawu zokuqala nezimpawu zomdlavuza we-gland gland, kanye nokwelashwa komdlavuza.

Funda ngale TAB yenodi yegland yegilo nokuthi kwenziwa kanjani ukuhlola okufundwe kuleli kheli.

Ezinye izimbangela zamazinga e-dihydrotestosterone akhuphukile:

• izigaxa ezilinganayo zezindlala zama-adrenal noma amaqanda,
• isakhi sofuzo
• ukukhulelwa
• ukuzwela kwezicubu okungekuhle kushukela, i-carbohydrate metabolism.

Ukubonakaliswa kwemitholampilo

Izimpawu zokukhiqiza ngokweqile kwe-dihydrotestosterone:

• izwi liba ngaphansi futhi liqeqeqebe
• umthambo ngesikhathi sokuthomba ukhula ngohlobo lowesilisa,
• ukuya esikhathini kuba yindlala, kungajwayelekile, noma i-amenorrhea iyakhula (ukungabikho kokuphuma kwegazi njalo ngenyanga),
• izinwele ziyancipha, zinciphise, i-alopecia zivame ukukhula,
• ukuphazamiseka kwezinqubo ezigabeni zomjikelezo wokuya esikhathini kuphazamisa ukuguqulwa kwama-follicles, ukukhishwa kweqanda. Uma kungekho ovulation, ukukhulelwa akunakwenzeka,
• ezingalweni nasemilenzeni, izinwele ezinamathele ziyaqina futhi kumnyama, kuqhume i-hirsutism, kuphakanyiswe imifino engafuneki ngenhla komlomo ophezulu nasendaweni yobuso,
• isisindo sizokwanda ngokushesha
• kukhona ukuhlaselwa kokungabekezeleleki nolaka olungenasisekelo,
• umsebenzi wezindlala ze-sebaceous uyanda, isikhumba siba oily, kuvela izinduna,
• ukushuba kongqimba lwamafutha okhalweni nasezinkalweni kuyehla, isiguli siba ngaphansi kwesifazane.

Qaphela! Isimo se-dihydrotestosterone kwabesifazane sisuka ku-24 siye ku-450 pg / ml. Izinkomba ziphansi kakhulu kunakwabesilisa (kusuka ku-250 kuye ku-990 pg / ml).

Imiphumela engaba khona

Ukwedlula isikhathi eside kwamazinga e-dihydrotestosterone kwabesifazane kungaholela emiphumeleni engathandeki:

• i-hirsutism
• amenorrhea
• ukungahambi kahle kokuya esikhathini,
• ushintsho esimweni sokuya esikhathini,
• isifo sikashukela
• ukukhuphuka kwezinwele ezinamafutha nesikhumba,
• Izinwele ezicwebezelayo,
• ukulahleka kobuntu besifazane
• ukuqina kwezwi
• ukuqwasha
• ukungasebenzi kahle kwe-carbohydrate metabolism, ukuthuthukiswa kwesifo sikashukela,
• ukukhuluphala
• i-polycystic ovary syndrome,
• ukungasebenzi kahle kokuzala.

Ungakuhlaziya kanjani nge-DHT

Ukucacisa izinga le-dihydrotestosterone, owesifazane kufanele afike elabhoratri esigabeni sokuqala somjikelezo. Isikhathi esifanele sisukela ezinsukwini ezi-4 kuye kweziyi-6.

Imithetho yokulungiselela:

• ngaphambi kokuhlaziywa (phakathi nosuku) awukwazi ukuphuza utshwala, kungakuhle ukuthi ungabi novalo. Ungazibandakanyi ejimini noma ungenzi umsebenzi wasengadini, ukusebenza ngokweqile,
• ngosuku olwandulela isifundo, ukudla kufanele kube lula, kunamafutha amancane,
• ekuseni awukwazi ukuphuza nokudla,
• zonke izidakamizwa kumele zithathwe ngemuva kokuphasa isivivinyo se-dihydrotestosterone,
• Ukuvakashela ilabhorethri kuyadingeka ekuseni, kungakapheli amahora ayi-11,
• ngaphambi kokuthatha igazi, udinga ukwehlisa umoya, uphumule ehhovisi imizuzu engu-15 ukuya ku-20,
• ngosuku lokufunda (ngaphambi kokufaka isampula ye-venous sampling) akunakwenzeka ukwenza i-ECG, i-X-ray ne-fluorogram, ukuthola ukwelashwa nge-massage kanye ne-physiotherapy.

Izindlela zokulungisa amazinga e-hormone

Lapho wembula amanani aphezulu e-dihydrotestosterone, udinga ukuthola imbangela yokuphambuka. Ngemuva kokuqeda isisusa esidabukisayo, udinga ushintsho ekudleni, uqinise isisindo ukuze wenze ngokwezifiso umzimba we-carbohydrate metabolism kanye nokulinganisela kwe-hormonal. Qiniseka ukuthi wehlisela umthwalo ohlelweni lwezinzwa, ubuyisele ibhalansi yengqondo ne-psycho

Udokotela kufanele acacisele ukuthi imiphi imishanguzo umuntu ayisebenzisayo. Uma kutholakala izidakamizwa ezikhuthaza ukukhiqizwa kwe-dihydrotestosterone, khona-ke udinga ukukhetha ama-analogues noma ukwenqaba ukuthatha izidakamizwa ezikhulisa izinga le-androgen elisebenzayo.

Ngokusho kokuqokwa kwe-endocrinologist noma i-gynecologist, kubalulekile ukuthi wenze inkambo yokwelashwa usebenzisa izindlela zokuvimbela inzalo ngomlomo. Amaphilisi anikeza umphumela omuhle: UJanine, uYarina. Ngokuphambuka okuncane kwe-DHT kokujwayelekile, isidakamizwa i-Femoden sinqunyelwe.

Ukuze unciphise ukuhlangana kwe-hormone yobulili yabesilisa, isiguli sithatha ukwakheka ngokusekelwe kwi-spironolactone kanye ne-metformin. Le mishanguzo uSiofor, Veroshpiron, iGlucofage ayiphazamisi nje kuphela ukuguqulwa kwe-testosterone ibe yi-dihydrotestosterone, kepha futhi inciphisa ushukela wegazi, ijwayele ukumuncwa kwe-glucose kanye ne-carbohydrate metabolism.

Ungayinciphisa kanjani i-testosterone kwabesifazane abangenawo ama-hormone ngezindlela zemvelo? Sinezimpendulo!

Ukuze uthole izimpawu ezithile nokwelashwa okusebenzayo kweHashimoto's thyroiditis, funda leli kheli.

Ekhasini http://vse-o-gormonah.com/vneshnaja-sekretsija/grudnye/listovidnaya-fibroadenoma.html funda ngalokho okuyi-fibroadenoma esakhiwe ngamaqabunga emithanjeni yezilwane ezincelisayo nokuthi ungaqeda kanjani imfundo.

Ukunciphisa ukuqoqwa kwe-dihydrotestosterone, kuyasiza ukusebenzisa imikhiqizo ene-phytoestrogens:

• izinto zobisi omuncu,
• imifino enamahlamvu
• kwahluma ukolweni
• uwoyela onziwe
• soya
• cherries
• okusanhlamvu
• uwoyela wemifino
• ubhontshisi
• i-Persimmon
• amantongomane.

Ukuze uzinze ibhalansi ye-hormonal, ukuthola ama-phytoestrogens, kubalulekile ukuphuza itiye ngokususelwa ku:

• peppermint
• amaqabunga amajikijolo
• Ivan ka-Ivan
• ama-marigolds
• amadayisi
• cuffs
• tsimitsifugi
• oregano
• alfalfa
• amagxolo esawow
• angelica
• isibabule.

Ngokuthuthukiswa kwe-hyperandrogenism, kuyadingeka ukuthi kuhlaziywe izinto lapho kukhuphuka khona izinga le-dihydrotestosterone.

Ukungaqiniseki komjikelezo wokuya esikhathini, ukukhula ngokweqile kwezinwele emzimbeni, ulaka olwedlulele nokuxineka, kanye nokukhula kokukhuluphala akunakwa.

Lapho ukuqoqwa kwe-dihydrotestosterone kuzinzile, ingozi yokuphazamiseka kwempilo yezala iyancipha, futhi nezimfuneko zokunciphisa ushukela we-glucose ziyancishiswa.

I-Dihydrotestosterone (DHT) kwabesifazane: kuyini, inqubo ejwayelekile yama-hormone, ukuthi wehla kanjani

Ukuthola ukuthi iyini i-dihydrotestosterone, njengoba sekuqondwe imisebenzi yayo esemqoka emzimbeni womuntu.

Elinye lama-hormone ebulili abesilisa abaluleke kakhulu yi-dihydrotestosterone (DHT). Ubhekele izinqubo ezibaluleke kakhulu ezenzeka emzimbeni womuntu:

• umsebenzi we-prostate osebenzayo
• ukuthuthukiswa okufanele kwezitho zangasese zangaphakathi nangaphandle,
• ukukhula kwemisipha efanayo,
• ukwakheka kohlelo lwamathambo,
• ukukhula kwezinwele
• okulawulwayo ngokuziphatha kobulili nokuqina.

I-Dihydrotestosterone nayo ikhiqizwa emzimbeni wesifazane. Onke ama-hormone ocansi abesilisa abizwa ngokuthi ama-androgen futhi akhiqizwa kwizindlala ze-adrenal Ama-hormone abesilisa ayadingeka kwabesifazane ukuba:

• umzimba
• ukukhula kwamathambo, izicubu, izinwele,
• ukulawulwa kwezindlala ze-sebaceous nezithukuthuku,
• ukwakheka kwe-libido.

Ukuphambuka ekukhiqizweni kwe-dihydrotestosterone emadodeni nakwabesifazane, bobabili ohlangothini lokwandisa ukugxilwa kwayo, kanye nokwehla kwesimo esijwayelekile, kungaholela ekwephulweni okukhulu komsebenzi wezinqubo ezahlukahlukene zomzimba.

Izinga lama-hormone emadodeni nakwabesifazane

Ukuthola ukuphambuka ekuqhekeni kwe-DHT emzimbeni, izinkomba zayo ezijwayelekile ziyasetshenziswa. Ukuhlushwa egazini kunqunywa ngokudlula ngokuhlaziywa komtholampilo, amanani atholakalayo aqhathaniswa nokujwayelekile.

Ithebula lezinkomba zesibonakaliso se-dihydrotestosterone samadoda nabesifazane ngeminyaka:

Amazinga we-hormone anciphile - izimbangela, izimpawu, izinketho zokwelashwa

Ukukhiqizwa kwe-DHT emzimbeni womuntu kungancipha ngaphansi kwethonya lezinto ezahlukahlukene:

• ukungasebenzi kwezitho zangasese
• i-prostatitis
• isifo sikashukela
• isimila emaqhugwaneni adrenal,
• ukuntuleka kwe-androgen
• onesifo sikaMorris,
• I-hypogonadism - ukungapheleli kwama-gonads.

I-Hypogonodism emadodeni

Ungaqaphelisisa impilo yakho bese uthatha izivivinyo ezinquma izinga lamahomoni ukuqala kwezimpawu ezilandelayo:

• ukulahlekelwa izinwele ngokuzumayo, ukuqedwa kokukhula kwabo,
• ukukhuluphala, kuboniswa ngohlobo lowesifazane (isisu, isifuba, okhalweni),
• ukungasebenzi kwe-erectile,
• Ukuntuleka kwe-sex drive,
• ukukhuphuka kokujuluka
• ukwehla kwesisindo semisipha
• isikhumba esomile
• ukukhathala, ukudangala, ukuqwasha,
• ukungazali

Ngokwesiko, odokotela balulekwa ukuthi bahlolwe uma okungenani kunezimpawu ezintathu ezingenhla.

Abafana, izinga eliphansi le-hormone liboniswa kanjena:

• ukuntuleka kwesisindo semisipha
• ukukhula kwezinwele okuhamba kancane, ukungabikho kwazo ebusweni, ezinqeni nasegunjini,
• ipenisi encishisiwe noma isakhiwo sayo esiyinqaba,
• kukhona ubufazi kulesi sibalo,
• ukuthuthukiswa okungafani nokuqina kwezitho.

Ungawandisa kanjani amazinga e-hormone?

Imvamisa, izinga eliphansi le-hormone libonakala emadodeni emva kweminyaka engama-30 ukuya kwengama-40 ubudala; izifo ezahlukahlukene zingakucasula lokhu. Uma i-hormone secretion itholakala ingaphansi kokujwayelekile, udinga ukuhlolwa okuningana ukukhomba i-pathologies eyinkimbinkimbi ngokwengeziwe. Ukwelashwa kufanele kuqala ngokususa imbangela yezimpande.

Futhi ukwandisa izinga le-dihydrotestosterone ye-hormone, i-endocrinologist ingakunikeza ukwelashwa okubuyiselwe ngemithi yokwenziwa equkethe i-testosterone.

Ukuguqulwa kweTestosterone kube yiDihydrotestosterone

Ezithanjeni eziphendula i-androgen, umsebenzi we-testosterone wanda kakhulu, futhi uqala ukuguqulela ku-dihydrotestosterone. Le nqubo ibizwa ngokuthi ukuguqulwa kwe-testosterone. I-enzyme engu-5-alpha reductase inegalelo elikhulu kulokhu kuguqulwa ngokungeza ama-athomu amabili e-hydrogen ekwakhiweni kwe-testosterone, yingakho i-hormone ibizwa ngokuthi yi-di-hydro-testosterone.

Ngesikhathi sokuguqulwa, isibopho phakathi kwe-testosterone ne-dihydrotestosterone siyachithwa, bese kwakhiwa i-steroid, enesibopho esiqinile nama-androgen receptors. Kungakho kunomthelela oqinile emzimbeni wesilisa noma sowesifazane.

Kungani kunokweqile kwehomoni

Ukuba khona kwe-prostate adenoma kuyimbangela evame kakhulu yokwanda kwe-dihydrotestosterone emadodeni.

Ekuqhubekeni kwezifundo zesayensi ezenziwa ngokubamba iqhaza kwabesilisa abaneminyaka engama-25 ukuya kwengama-40, kwavela ukuthi wonke umuntu owayephethwe yi-Prostate adenoma wayenyuse i-dihydrotestosterone.

Njengomphumela wokukhula kwesimila esinciphile sezicubu ze-Prostate, sikhula ngosayizi bese sikhiqiza ama-hormone amaningi.

Imiphumela yokwanda okungajwayelekile kokuqunjelwa kwe-hormone emzimbeni wesilisa:

• izimpandla, ukulahleka kwezinwele okungazelelwe,
• ukubukeka komqubuko
• ukungaphatheki kahle
• enolaka, nokuziphatha okunobudlova
• ukungazali kwakheka ngokumelene nokuqina kwamathambo

Ngokunyuka kwe-dihydrotestosterone kwabesifazane, umzimba usabela ngokuhlukile, kukhona:

• ukukhula kwezinwele okuthuthukisiwe ebusweni, emzimbeni, uhlobo lowesilisa,
• ukujuluka ngokweqile
• ukukhululeka okukhuphukile kwezindlala zesikhumba
• isifo se-metabolic, futhi ngenxa yalokho - ukukhuluphala,
• intombazane ingazizwa ikhuphuka i-sex drive,
• ukwehluleka kokuya esikhathini
• ukwanda kosayizi be-clitoris ne-labia.

Uma i-dihydrotestosterone iphakanyisiwe kwabesifazane, khona-ke lokhu kungakhombisa izifo ezinkulu:

• isimila se-adrenal,
• ukungazali
• i-hirsutism.

Izizathu zokwanda kwamazinga ama-hormone abesifazane:

• isimila esibelethweni,
• ukungondleki, ukukhuluphala,
• ukuthatha ezinye izidakamizwa ze-hormonal,
• Izifo ezizalwe kabusha noma ze-hypothalamus.

I-sensensivity to dihydrotestosterone ibonwa kwabesifazane abanesifo sikashukela sohlobo 2.

I-Hormone blocker

Ukuze unciphise izinga le-dihydrotestosterone, kuyadingeka ukuvimba ukunciphisa i-5-alpha reductase. Ngenxa yale enzyme, ukuguqulwa kwe-testosterone ku-DHT kwenzeka. I-Dihydrotestosterone nokulahleka kwezinwele kuyimibono emibili ehlobene, ngoba ukukhiqizwa kwe-enzyme kuncike ekusebenzeni kwama-follicles wezinwele.

Kungakho, ngokwephula ukukhiqizwa kwama-hormone, izinwele ziphuma. Izidakamizwa ezibekelwe ukwehlisa izinga le-dihydrosterone zibizwa ngokuthi ama-5-alpha reductase blockers. Okuvame kakhulu yilezi:

Ngaphezu kwezidakamizwa zokwenziwa, ama-phytoestrogens asetshenziselwa ukwehlisa ukukhiqizwa kwama-hormone:

• izithelo zesundu ezimfushane zinama-acid anamafutha, ama-resins, kanye nama-tannins, anciphisa umsebenzi wezicucwana zezinwele,
• Ishaye i-nettle
• i-clover ebomvu
• soya
• alfalfa.

Izidakamizwa zabesifazane zehlisa i-androgen

Uma i-dihydrotestosterone kwabesifazane iphezulu, khona-ke udokotela ohambelayo angakunikeza le mithi elandelayo:

Lezi zidakamizwa ezimbili azivimbi kuphela isenzo se-androgens, kepha zivimbela umkhiqizo wazo.

Imvamisa, odokotela bangakunikeza ezinye izindlela zokuvimbela inzalo:

Ukwehlisa izinga le-hormone ngendlela yemithi, kunconywa ukusebenzisa ama-decoctions amakhambi:

Ukwanda kwe-dihydrotestosterone kwabesifazane - izimbangela nezindlela zokwelashwa

I-dihydrotestosterone ephakanyisiwe kwabesifazane yenzeka ngezizathu ezahlukahlukene.

Kwezinye izimo, lokhu kuchazwa yinkambiso yezinqubo zemvelo zemvelo, kwezinye - ngokuba khona kwe-pathologies emzimbeni.

Kuyadingeka ukuhlukanisa lapho ushintsho ngemuva kwesizinda se-hormonal lungokwesikhashana futhi lungazibeki ebungozini, nalapho kudingeka usizo lwezokwelashwa.